SYNTHESIS OF 2',3'-DISUBSTITUTED 3'-DEOXYTHYMIDINE DERIVATIVES
Reaction of 2 with DAST followed by detritylation and monomethoxytritylation afforded 34percent of the fluorinated nucleoside 3.This intermediate was used to prepare the 3'-azido-2'-fluoro- and 2',3'-difluoro substituted 5-methyluridine analogues 7 and 11, respectively.
Herdewijn, P.,Aerschot, A. Van
p. 943 - 948
(2007/10/02)
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