1206968-92-4

Basic information

• Product Name: 5-Bromo-3-fluoro-2-(hydro...
• Synonyms: 5-Bromo-3-fluoro-2-(hydro...;5-BroMo-3-fluoro-2-(hydroxyMethyl)pyridine;(5-broMo-3-fluoropyridin-2-yl)Methanol;(5-Bromo-3-fluoro-2-pyridyl)methanol
• CAS NO: 1206968-92-4
• Molecular Formula: C6H5BrFNO
• Molecular Weight: 206.0124032
• Mol File: 1206968-92-4.mol

Chemical Properties

• Boiling Point: 245.8±35.0 °C(Predicted)
• Appearance: /
• Density: 1.762±0.06 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 12.35±0.10(Predicted)
• CAS DataBase Reference: 5-Bromo-3-fluoro-2-(hydro...(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-3-fluoro-2-(hydro...(1206968-92-4)
• EPA Substance Registry System: 5-Bromo-3-fluoro-2-(hydro...(1206968-92-4)

Safety Data

• Hazardous Substances Data: 1206968-92-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
5-Bromo-3-fluoro-2-(hydroxyimino)benzaldehyde is used as a key intermediate in the synthesis of pharmaceutical compounds for its ability to interact with biological targets, contributing to the development of potential drugs.
Used in Agrochemical Synthesis:
In the agrochemical industry, 5-Bromo-3-fluoro-2-(hydroxyimino)benzaldehyde is utilized as a building block for the creation of various agrochemicals, enhancing their effectiveness in agricultural applications.
Used in Medicinal Chemistry and Drug Discovery:
5-Bromo-3-fluoro-2-(hydro... plays a significant role in medicinal chemistry and drug discovery, where it is employed as a structural component in the design and synthesis of novel therapeutic agents.
Used in the Production of Dyes and Pigments:
5-Bromo-3-fluoro-2-(hydroxyimino)benzaldehyde is also used as a precursor in the production of dyes and pigments, contributing to the coloration and properties of various specialty chemicals.

Upstream product

• 1211538-72-5 methyl 5-bromo-3-fluoro-pyridine-2-carboxylate 
• 669066-91-5 5-bromo-3-fluoro-pyridine-2-carboxylic acid 
• 886373-28-0 5-bromo-3-fluoropyridine-2-carbonitrile 

Downstream Products

• 1234616-19-3 (5-bromo-3-fluoropyridin-2-yl)methanamine 

Relevant articles and documents

5-FLUORONICOTINAMIDE DERIVATIVES AND USES THEREOF

Provided herein is a compound of Formula (I), or pharmaceutically acceptable salt thereof, wherein R1, Y, X, and n are defined herein. Also provided herein are compositions comprising a compound of Formula (I) or pharmaceutically acceptable salt thereof, and methods of using a compound of Formula (I) or pharmaceutically acceptable salt thereof, e.g., in the treatment of heart disease.

IMIDAZOLE AND TRIAZOLE CONTAINING BICYCLIC COMPOUNDS AS JAK INHIBITORS

The invention provides compounds of formula (I): or a pharmaceutically-acceptable salt thereof, wherein the variables are defined in the specification, that are inhibitors of JAK kinases, particularly JAK3. The invention also provides pharmaceutical compo

FATTY ACID SYNTHASE INHIBITORS

This invention relates to novel spirocyclic piperidines according to Formula (I) which are inhibitors of fatty acid synthase (FAS), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.

ANTIDIABETIC BICYCLIC COMPOUNDS

Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

THIAZALOPYRROLIDINE INHIBITORS OF ROR-GAMMA

Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

GPR119 AGONIST

A cyclic amine derivative represented by the formula (II) is a GPR119 agonist, and is used as an agent for treating diabetes. wherein Ar0 is phenyl or phenyl having a substituent such as C1-8 alkylsulfonyl or the like, pyridyl, or pyridyl having a substituent such as C1-8 alkylsulfonyl; A0 is (CH2)p, O, or the like; B0 is (CH2)q, or the like, provided that B0 is neither O nor NR25 when A0 is O or NR24; one of U0 and V0 is N, and the other is N or CR26; each of X0\ and Y0 is C1-3 alkylene or C1-3 alkylene having a substituent; R23 is a C1-8 alkyl group or the like; each of R21 and R22 is hydrogen, a halogen atom, or the like.