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1210854-81-1

C25H22F4N2O is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1210854-81-1 Structure

  • Basic information

    1. Product Name: C25H22F4N2O
    2. Synonyms:
    3. CAS NO:1210854-81-1
    4. Molecular Formula:
    5. Molecular Weight: 442.456
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1210854-81-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C25H22F4N2O(CAS DataBase Reference)
    10. NIST Chemistry Reference: C25H22F4N2O(1210854-81-1)
    11. EPA Substance Registry System: C25H22F4N2O(1210854-81-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1210854-81-1(Hazardous Substances Data)

1210854-81-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1210854-81-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,0,8,5 and 4 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1210854-81:
(9*1)+(8*2)+(7*1)+(6*0)+(5*8)+(4*5)+(3*4)+(2*8)+(1*1)=121
121 % 10 = 1
So 1210854-81-1 is a valid CAS Registry Number.

1210854-81-1Downstream Products

1210854-81-1Relevant articles and documents

Arylglycine derivatives as potent transient receptor potential melastatin 8 (TRPM8) antagonists

Zhu, Bin,Xia, Mingde,Xu, Xiaoqing,Ludovici, Donald W.,Tennakoon, Manomi,Youngman, Mark A.,Matthews, Jay M.,Dax, Scott L.,Colburn, Raymond W.,Qin, Ning,Hutchinson, Tasha L.,Lubin, Mary Lou,Brandt, Michael R.,Stone, Dennis J.,Flores, Christopher M.,MacIelag, Mark J.

, p. 2234 - 2237 (2013/04/23)

A series of arylglycine-based analogs was synthesized and tested for TRPM8 antagonism in a cell-based functional assay. Following structure-activity relationship studies in vitro, a number of compounds were identified as potent TRPM8 antagonists and were subsequently evaluated in an in vivo pharmacodynamic assay of icilin-induced 'wet-dog' shaking in which compound 12 was fully effective. TRPM8 antagonists of the type described here may be useful in treating pain conditions wherein cold hypersensitivity is a dominant feature.

Cold Menthol Receptor Antagonists

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Page/Page column 56-57, (2010/03/31)

Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: wherein A, B, L, Q, R1, R2, and R3 /s

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