121246-93-3

Basic information

• Product Name: Ethanone, 1-(3-aminopyrazinyl)- (9CI)
• Synonyms: Ethanone, 1-(3-aminopyrazinyl)- (9CI);1-(3-aMinopyrazin-2-yl)ethanone;1-(3-Aminopyrazin-2-yl)ethan-1-one;2-Amino-3-acetylpyrazine
• CAS NO: 121246-93-3
• Molecular Formula: C6H7N3O
• Molecular Weight: 137.13928
• EINECS: 604-604-1
• Product Categories: ACETYLGROUP
• Mol File: 121246-93-3.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: Ethanone, 1-(3-aminopyrazinyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(3-aminopyrazinyl)- (9CI)(121246-93-3)
• EPA Substance Registry System: Ethanone, 1-(3-aminopyrazinyl)- (9CI)(121246-93-3)

Safety Data

• Hazardous Substances Data: 121246-93-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Development:
Ethanone, 1-(3-aminopyrazinyl)(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals for its potential to contribute to the development of new drugs. Its unique structure allows it to be a versatile component in the creation of a wide range of medicinal compounds.
Used in Organic Synthesis:
In the field of organic synthesis, Ethanone, 1-(3-aminopyrazinyl)(9CI) is utilized as a reagent or a precursor for the formation of complex organic molecules. Its ability to participate in various chemical reactions makes it a valuable asset in the synthesis of specialty chemicals and advanced materials.
Used in Chemical Reactions and Mechanism Studies:
Ethanone, 1-(3-aminopyrazinyl)(9CI) is employed as a model compound in the study of chemical reactions and mechanisms. Understanding its behavior in different reaction conditions can provide insights into the broader principles of organic chemistry and catalysis.
Used in Biological Activity and Pharmacological Property Research:
Ethanone, 1-(3-aminopyrazinyl)(9CI) is also used in research aimed at exploring its biological activity and pharmacological properties. This research can lead to the discovery of new therapeutic agents or a better understanding of the compound's interactions with biological systems.

Upstream product

• 121246-90-0 3-Chloro-2-pyrazinyl methyl ketone 
• 854892-35-6 N-(3-acetylpyrazin-2-yl)acetamide 
• 5424-01-1 3-aminopyrazinoic acid 
• 37706-71-1 2-methylpyrazine<2,3-d><1,3>oxazine-4-one 
• 121246-84-2 (rac)-1-(3-chloropyrazin-2-yl)ethan-1-ol 

Downstream Products

• 226559-50-8 3-acetamido-2-pyrazinecarboxylic acid 

Relevant articles and documents

Structural characterisation of 2,3-disubstituted pyrazines: NMR and X-ray crystallography

2-Formyl-3-aminopyrazine (1), 2-acetyl-3-aminopyrazine (2) and 2-benzoyl-3-aminopyrazine (3) have been studied by multinuclear magnetic resonance spectroscopy in solution and in solid state. Amino-imine tautomerism in such derivatives has been discussed on the basis of the calculated stabilities of the different tautomers by the hybrid B3LYP/6-31G** method. The crystalline structure of compound 3 has been solved, it belongs to the monoclinic P21/n space group, and shows supramolecular architectures involving N-H?O and N-H?N-pyrazine intermolecular hydrogen bonds.

A New Route to 2,3-Disubstituted Pyrazines; Regioselective Metalation of Chloropyrazine

Chloropyrazine is regioselectively metalated by lithium amides in tetrahydrofuran to give 3-chloro-2-lithiopyrazine.The reaction of this lithio derivative with electrophiles can either be performed in situ (with the electrophile, e.g., chlorotrimethylsila