12163-21-2Relevant articles and documents
TRICYCLIC COMPOUND SERVING AS IMMUNOMODULATOR
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Paragraph 0298-0299, (2019/01/04)
Provided are compounds of formula I and formula II or pharmaceutically acceptable salts of the compounds and pharmaceutical compositions thereof. The compounds of formula I and formula II or the pharmaceutically acceptable salts of the compounds provide indole 2,3-dioxygenase (IDO) inhibitory activity and are capable of treating IDO-mediated immunosuppressive diseases, such as infectious diseases or cancer.
CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS
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Page/Page column 44-45, (2012/03/26)
The invention relates to the cycloalkyl methoxybenzyl phenyl pyran derivatives as Sodium dependent glucose co transporter (SGLT) inhibitors, particularly SGLT2 and method of treating diseases, conditions and/or disorders inhibited by SGLT2 with them, and processes for preparing them.
Fluorinated carbocylic compounds
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, (2008/06/13)
Fluoro-substituted carbocyclic compounds are prepared by (A) reacting hydrogen fluoride with a chloro-cyclohexenyl compound of the formula STR1 where R1 and R2 are independently selected from the group consisting of --H, --CH2 OH, --COF, --COCl, --CF3, --CN, STR2 and --CH2 R, where R is --H or alkyl of 1-4 carbon atoms, to form a gem-dihalocyclohexane compound of the formula STR3 where X is chlorine and R1 and R2 are as defined above, (B) dehydrohalogenating the gem-dihalocyclohexane compound in the vapor phase to form a fluoro-cyclohexenyl compound of the formula STR4 (C) contacting the fluoro-cyclohexenyl compound, in the vapor phase, with a dehydrogenation catalyst to form a fluoro-substituted aromatic compound of the formula STR5