122980-86-3Relevant articles and documents
An Efficient Method for the Synthesis of Trifluoromethyl Substituted Heterocycles
Linderman, Russell J.,Kirollos, S. Kirollos
, p. 2049 - 2052 (1989)
Trifluoromethyl substituted pyrazoles and isoxazoles have been prepared regiospecifically in high yield from trifluoroacetyl acetylenes.
In Situ Generated Fluorinated Iminium Salts for Difluoromethylation and Difluoroacetylation
Schmitt, Etienne,Rugeri, Baptiste,Panossian, Armen,Vors, Jean-Pierre,Pazenok, Sergii,Leroux, Frédéric R.
supporting information, p. 4510 - 4513 (2015/09/28)
The use of TFEDMA, a fluoroalkyl amino reagent, for the difluoromethylation and difluoroacylation of arenes, heteroarenes, and C-H acidic compounds is reported. This approach allows for an efficient access to difluoromethylated products of high added valu