1232431-75-2

Basic information

• Product Name: 2,3-Diamino-4-bromopyridine
• Synonyms: 2,3-Diamino-4-bromopyridine;4-BroMo-2,3-diaMinopyridine;4-broMopyridine-2,3-diaMine;4-broMopyridine-2
• CAS NO: 1232431-75-2
• Molecular Formula: C₅H₆BrN₃
• Molecular Weight: 188.02524
• Mol File: 1232431-75-2.mol

Chemical Properties

• Melting Point: 154-155 °C
• Boiling Point: 341.6±37.0 °C(Predicted)
• Appearance: /
• Density: 1.818±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 5.68±0.47(Predicted)
• CAS DataBase Reference: 2,3-Diamino-4-bromopyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Diamino-4-bromopyridine(1232431-75-2)
• EPA Substance Registry System: 2,3-Diamino-4-bromopyridine(1232431-75-2)

Safety Data

• Hazardous Substances Data: 1232431-75-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,3-Diamino-4-bromopyridine is used as an intermediate compound for the synthesis of various drugs. Its unique structure and reactivity make it a valuable building block in the development of new pharmaceuticals.
Used in Dye Industry:
2,3-Diamino-4-bromopyridine is used as a chemical intermediate in the production of dyes. Its ability to participate in chemical reactions allows for the creation of a wide range of dye colors and properties.
Note: The toxicity and environmental impact of 2,3-Diamino-4-bromopyridine are not extensively studied, and hence, care should be taken while handling it.

InChI:InChI=1S/C5H6BrN3/c6-3-1-2-9-5(8)4(3)7/h1-2H,7H2,(H2,8,9)

Upstream product

• 13269-19-7 3-amino-2-nitropyridine 
• 1305317-30-9 3-amino-4-bromo-2-nitropyridine 
• 1072-97-5 5-bromo-2-pyridylamine 
• 84249-02-5 2-nitroamino-4-bromopyridine 
• 84487-10-5 2-amino-4-bromo-3-nitropyridine 

Downstream Products

• 1305317-33-2 8-azido-2,3-diphenylpyrido[2,3-b]pyrazine 
• 1305317-34-3 8-azido-2,3-bis(4-methoxyphenyl)pyrido[2,3-b]pyrazine 
• 1305317-35-4 8-amino-2,3-diphenylpyrido[2,3-b]pyrazine 
• 1305317-36-5 8-amino-2,3-bis(4-methoxyphenyl)pyrido[2,3-b]pyrazine 
• 1305317-37-6 N-(2,3-diphenylpyrido[2,3-b]pyrazin-8-yl)-N'-ethylurea 
• 1305317-38-7 N-(2,3-diphenylpyrido[2,3-b]pyrazin-8-yl)-N'-phenylurea 
• 1305317-39-8 N-(3-chlorophenyl)-N'-(2,3-diphenylpyrido[2,3-b]pyrazin-8-yl)urea 
• 1305317-40-1 N-[2,3-bis(4-methoxyphenyl)pyrido[2,3-b]pyrazin-8-yl]-N'-ethylurea 
• 1305317-41-2 N-[2,3-bis(4-methoxyphenyl)pyrido[2,3-b]pyrazin-8-yl]-N'-phenylurea 
• 1305317-42-3 N-(2,3-diphenylpyrido[2,3-b]pyrazin-8-yl)-N'-ethylthiourea 
• 1305317-43-4 N-(2,3-diphenylpyrido[2,3-b]pyrazin-8-yl)-N'-phenylthiourea 
• 1305317-32-1 8-bromo-2,3-bis(4-methoxyphenyl)pyrido[2,3-b]pyrazine 
• 1305317-31-0 8-bromo-2,3-diphenylpyrido[2,3-b]pyrazine 

Relevant articles and documents

BIARYL KINASE INHIBITORS

The present disclosure is directed to biaryl compounds of formula (I) which can inhibit AAKl (adaptor associated kinase 1), compositions comprising such compounds and their use for treating e.g. pain, Alzheimer's disease, Parkinson's disease and schizophrenia.

A model D - amino acid oxidase inhibitor and its preparation and application

The invention provides a novel D- amino acid oxidase inhibitor and a preparation and application thereof. In particular, the invention discloses derivatives of quinoxaline-2,3-diketone, which has a novel structure shown in formula A, as well as a preparation method thereof and an application as an inhibitor of D-amino acid oxidase (DAAO). The compound provided by the invention shows excellent effects of analgesia and blocking morphine analgesia tolerance, and has application value for analgesia, treating opiate drug tolerance, and anti-schizophrenia.

Preparation of novel 2,3,8-trisubstituted pyrido[3,4-b]pyrazines and pyrido[2,3-b]pyrazines

A four-step synthesis of 8-bromo-2,3-disubstituted pyrido[3,4-b]pyrazines and a six-step synthesis of 8-amino-2,3-disubstituted pyrido[3,4-b]pyrazines have been developed. A particularly valuable feature of this synthetic route is the possibility to build