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1235280-35-9

(R)-N-Acetyl-6-Chloro-Trp-OMe is a chemical compound derived from the amino acid tryptophan, featuring an acetyl group and a chloro group attached to the tryptophan molecule. This modification endows it with unique properties that make it valuable in research and pharmaceutical applications.

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  • 1235280-35-9 Structure

  • Basic information

    1. Product Name: (R)-N-Acetyl-6-Chloro-Trp-OMe
    2. Synonyms: (R)-N-Acetyl-6-Chloro-Trp-OMe;(R)-methyl 2-acetamido-3-(6-chloro-1H-indol-3-yl)propanoate;-Methyl 2-acetamido-3-(6-chloro-1H-indol-3-yl)
    3. CAS NO:1235280-35-9
    4. Molecular Formula: C14H15ClN2O3
    5. Molecular Weight: 294.7335
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1235280-35-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: (R)-N-Acetyl-6-Chloro-Trp-OMe(CAS DataBase Reference)
    10. NIST Chemistry Reference: (R)-N-Acetyl-6-Chloro-Trp-OMe(1235280-35-9)
    11. EPA Substance Registry System: (R)-N-Acetyl-6-Chloro-Trp-OMe(1235280-35-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1235280-35-9(Hazardous Substances Data)

1235280-35-9 Usage

Uses

Used in Research Applications:
(R)-N-Acetyl-6-Chloro-Trp-OMe is used as a research tool for studying the structure and function of bioactive peptides. Its unique chemical properties allow scientists to investigate its interactions with biological systems and understand its potential role in various cellular processes.
Used in Pharmaceutical Development:
In the pharmaceutical industry, (R)-N-Acetyl-6-Chloro-Trp-OMe is utilized in the development of new drugs. Its ability to interact with biological systems suggests that it may have therapeutic properties, which are currently being explored in ongoing scientific studies. (R)-N-Acetyl-6-Chloro-Trp-OMe holds promise for the creation of innovative treatments that could address a range of health conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 1235280-35-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,5,2,8 and 0 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1235280-35:
(9*1)+(8*2)+(7*3)+(6*5)+(5*2)+(4*8)+(3*0)+(2*3)+(1*5)=129
129 % 10 = 9
So 1235280-35-9 is a valid CAS Registry Number.

1235280-35-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl (2R)-2-acetamido-3-(6-chloro-1H-indol-3-yl)propanoate

1.2 Other means of identification

Product number -
Other names (R)-N-ACETYL-6-CHLORO-TRP-OME

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1235280-35-9 SDS

1235280-35-9Downstream Products

1235280-35-9Relevant articles and documents

A fast and direct iodide-catalyzed oxidative 2-selenylation of tryptophan

Gao, Yu-Ting,Liu, Shao-Dong,Cheng, Liang,Liu, Li

supporting information, p. 3504 - 3507 (2021/04/12)

A metal-free 2-selenylation of tryptophan derivatives is reported, where the use of iodide as the catalyst and oxone as the oxidant is key to obtain high yields. Various functional groups within the di-seleny and the indole ring are tolerated, and no racemization is generally observed.

Enantioselective Synthesis of Fused Polycyclic Tropanes via Dearomative [3 + 2] Cycloaddition Reactions of 2-Nitrobenzofurans

Wang, Zhen,Wang, Dong-Chao,Xie, Ming-Sheng,Qu, Gui-Rong,Guo, Hai-Ming

supporting information, p. 164 - 167 (2020/01/11)

A straight synthetic approach to fused polycyclic tropane scaffold formation through an asymmetric dearomatization cycloaddition process of 2-nitrobenzofurans with cyclic azomethine ylides was successfully developed. In the presence of a chiral copper com

Synthesis and biological evaluation of novel tryptoline derivatives as indoleamine 2,3-dioxygenase (IDO) inhibitors

Tanaka, Minoru,Li, Xin,Hikawa, Hidemasa,Suzuki, Takafumi,Tsutsumi, Katsuhiko,Sato, Masashi,Takikawa, Osamu,Suzuki, Hideharu,Yokoyama, Yuusaku

, p. 1159 - 1165 (2013/03/14)

Indoleamine 2,3-dioxygenase (IDO) plays a significant role in several disorders such as Alzheimer's disease, age-related cataracts and tumors. A series of novel tryptoline derivatives were synthesized and evaluated for their inhibitory activity against ID

Switchable reactivity of acylated α,β-dehydroamino ester in the Friedel-Crafts alkylation of indoles by changing the lewis acid

Angelini, Elena,Balsamini, Cesarino,Bartoccini, Francesca,Lucarini, Simone,Piersanti, Giovanni

, p. 5654 - 5657 (2008/12/21)

(Chemical Equation Presented) Highly regioselective electrophilic substitution of indoles with N-acetylated α,β-dehydroalanine methyl ester, promoted by different transition metal salts was achieved. The orthogonal regioselectivity provides an efficient p

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