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N-[4-(PIPERIDIN-4-YLCARBONYL)PHENYL]ACETAMIDE 97, also known as NPPA 97, is a piperidinyl butyrophenone derivative and a selective sigma-1 agonist. It is a chemical compound used in research settings for its potential as an antipsychotic and antidepressant agent, as well as for its neuroprotective and anticonvulsant properties. NPPA 97 has been found to modulate the release of dopamine and other neurotransmitters in the brain, making it a promising target for further investigation in the treatment of neurological and psychiatric disorders. However, its precise mechanisms of action and potential therapeutic applications are still under study.

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  • 124035-23-0 Structure
  • Basic information

    1. Product Name: N-[4-(PIPERIDIN-4-YLCARBONYL)PHENYL]ACETAMIDE 97
    2. Synonyms: N-[4-(PIPERIDINE-4-CARBONYL)-PHENYL]-ACETAMIDE;N-[4-(PIPERIDIN-4-YLCARBONYL)PHENYL]ACETAMIDE 97;N-[4-(Piperidin-4-ylcarbonyl)phenyl]acetamide;N-[4-(Piperidin-4-ylcarbonyl)phenyl]acetamide 97%;4'-(Piperidin-4-ylcarbonyl)acetanilide 97%;Acetamide, N-[4-(4-piperidinylcarbonyl)phenyl]-;4'-(Piperidin-4-ylcarbonyl)acetanilide97%;4-(Piperidin-4-ylcarbonyl)acetanilide
    3. CAS NO:124035-23-0
    4. Molecular Formula: C14H18N2O2
    5. Molecular Weight: 246.30492
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 124035-23-0.mol
  • Chemical Properties

    1. Melting Point: 171 °C
    2. Boiling Point: 482.3°Cat760mmHg
    3. Flash Point: 194.1°C
    4. Appearance: /
    5. Density: 1.158g/cm3
    6. Vapor Pressure: 1.85E-09mmHg at 25°C
    7. Refractive Index: 1.575
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: N-[4-(PIPERIDIN-4-YLCARBONYL)PHENYL]ACETAMIDE 97(CAS DataBase Reference)
    11. NIST Chemistry Reference: N-[4-(PIPERIDIN-4-YLCARBONYL)PHENYL]ACETAMIDE 97(124035-23-0)
    12. EPA Substance Registry System: N-[4-(PIPERIDIN-4-YLCARBONYL)PHENYL]ACETAMIDE 97(124035-23-0)
  • Safety Data

    1. Hazard Codes: C
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 124035-23-0(Hazardous Substances Data)

124035-23-0 Usage

Uses

Used in Pharmaceutical Research:
NPPA 97 is used as a research compound for its potential as an antipsychotic and antidepressant agent. It is being studied for its ability to modulate the release of neurotransmitters in the brain, which could contribute to the development of new treatments for neurological and psychiatric disorders.
Used in Neuroprotective Applications:
NPPA 97 is used as a neuroprotective agent due to its potential to protect neurons from damage and degeneration. Its neuroprotective properties make it a candidate for further investigation in the treatment of neurodegenerative diseases.
Used in Anticonvulsant Applications:
NPPA 97 is used as an anticonvulsant agent, as it has been found to possess properties that can help prevent or reduce the severity of seizures. This makes it a potential candidate for the development of new treatments for epilepsy and other seizure disorders.
Used in Drug Development for Neurological Disorders:
NPPA 97 is used as a target for drug development in the treatment of neurological disorders. Its ability to modulate neurotransmitter release and its neuroprotective and anticonvulsant properties make it a promising candidate for the development of new therapies for conditions such as Parkinson's disease, Alzheimer's disease, and other neurological disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 124035-23-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,0,3 and 5 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 124035-23:
(8*1)+(7*2)+(6*4)+(5*0)+(4*3)+(3*5)+(2*2)+(1*3)=80
80 % 10 = 0
So 124035-23-0 is a valid CAS Registry Number.
InChI:InChI=1/C14H18N2O2/c1-10(17)16-13-4-2-11(3-5-13)14(18)12-6-8-15-9-7-12/h2-5,12,15H,6-9H2,1H3,(H,16,17)

124035-23-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[4-(piperidine-4-carbonyl)phenyl]acetamide

1.2 Other means of identification

Product number -
Other names N-[4-(Piperidin-4-ylcarbonyl)phenyl]acetamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:124035-23-0 SDS

124035-23-0Downstream Products

124035-23-0Relevant articles and documents

ANTITHROMBOTIC COMPOUNDS

-

, (2008/06/13)

The present invention is directed to a new class of piperidinyl medicinal agents which are useful as antithrombotic agents and as serotonin 5HT 2 antagonists.

N-aralkyl piperidine derivatives useful as antithrombolytic agents

-

, (2008/06/13)

The present invention is directed to a new class of compounds useful as antiarrhythmics, analgesics and serotonin 5HT2 antagonists, which compounds have the following formula: STR1 wherein; Y is represented by H, CO(CH2)n CH3 in which n is an integer from 0-3, or SO2 (CH2)n CH3 in which n is an integer from 0--3; X is represented CO, CHOH, or C=N--O--A, wherein A is represented by hydrogen or a C1-4 alkyl; R is either selected from the group consisting of halogens, lower alkyl groups, lower alkoxy groups, and hydrogen or R is a divalent substituent and is represented by a 3,4-methylenedioxy or a 3,4-ethylenedioxy substituent; m is an integer from 1-5; and the pharmaceutically acceptable acid addition salts thereof.

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