- Development of hydrophilic polyacrylamide gel-based condensing reagents comprised of chlorotriazine
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Hydrophilic polyacrylamide gel-based triazine-type condensing reagents, PAG-Trz-Cl, have been developed. PAG-Trz-Cls were synthesized using a chlorotriazine with an acrylamide moiety, acrylamide, and N,N'-methylenebisacrylamide via both precipitation and
- Yamada, Kohei,Hirozawa, Shota,Xia, Junqing,Kunishima, Munetaka
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p. 534 - 537
(2020/07/31)
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- Method for synthesizing amide compounds by using N-Boc amide as substrate
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The invention relates to a method for synthesizing amide compounds by using N-Boc amide as a substrate. According to the method, N-Boc amide and various amine compounds are subjected to an intermolecular nucleophilic substitution reaction in an organic solvent so as to efficiently prepare various amide compounds. The method has the advantages of mild reaction conditions, simple and convenient operation, high yield and good functional group compatibility.
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Paragraph 0193-0201
(2020/01/12)
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- MRI sensing of neurotransmitters with a crown ether appended Gd3+ complex
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Molecular magnetic resonance imaging (MRI) approaches that detect biomarkers associated with neural activity would allow more direct observation of brain function than current functional MRI based on blood-oxygen-level-dependent contrast. Our objective wa
- Oukhatar, Fatima,Même, Sandra,Même, William,Szeremeta, Frédéric,Logothetis, Nikos K.,Angelovski, Goran,Tóth, éva
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p. 219 - 225
(2015/03/04)
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- DNA CONTROLLED ASSEMBLY OF LIPID MEMBRANES
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The present invention relates to detection of target nucleic acids by targetnucleic acid induced liposome assembly. The invention provides oligonucleotides for use in detection and a method of detecting target nucleic acids.Other aspects of the invention
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Page/Page column 18-19
(2008/12/07)
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- Toward a catalytic site in DNA: Polyaza crown ether as non-nucleosidic building blocks in DNA conjugates
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A number of functionalized polyaza crown ether building blocks have been incorporated into DNA-conjugates as catalytic Cu2+ binding sites. The effect of the DNA-conjugate catalyst on the stereochemical outcome of a Cu2+-catalyzed Diels-Alder reaction will
- Jakobsen, Ulla,Rohr, Katja,Vogel, Stefan
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p. 1419 - 1422
(2008/09/20)
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- A substituted triaza crown ether as a binding site in DNA conjugates
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Synthesis of an asymmetrically substituted triaza crown ether, its incorporation into the 3′-end and 5′-end of nine-mer oligonucleotides, and the influence of various alkanediamine ligands on duplex thermostabilities are reported.
- Vogel, Stefan,Rohr, Katja,Dahl, Otto,Wengel, Jesper
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p. 1006 - 1007
(2007/10/03)
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- Synthesis of an asymmetrically substituted AZA crown ether as metal and amino acid binding site in DNA conjugates
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Crown ether 4 as a receptor core for protonated primary amines such as amino acids has been synthesized and incorporated into oligodeoxynucleotides as dangling ends.
- Vogel, Stefan,Rohr, Katja,Dahl, Otto,Wengel, Jesper
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p. 1039 - 1040
(2007/10/03)
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- N-acyldipeptides, processes for the preparation thereof and pharmaceutical compositions containing the same
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N-acyldipeptides of formula I STR1 wherein R represents a rest of formula STR2 and R4, Y, m, n and Z have the meaning as defined in the description, R1 represents hydrogen, a 1-10 C. alkyl, an optionally substituted methyl or benzyl,
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- A New Building Block Method to Synthesize Symmetrical and Asymmetrical Per-N-alkyl-Substituted Polyaza-Crown Compounds
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A new approach for the synthesis of a variety of per-N-alkylated polyaza-crown compounds is decscribed.N-acetamide (25) and its benzamide analogue 26 are the key building blocks for the synthesis of the new polyaza-crowns.These ch
- Krakowiak, Krzysztof E.,Bradshaw, Jerald S.,Izatt, Reed M.,Zamecka-Krakowiak, Daria J.
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p. 4061 - 4067
(2007/10/02)
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