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1-(4-iodophenyl)cyclopropanecarbonitrile is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

124276-79-5

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124276-79-5 Usage

Chemical class

Belongs to the class of cyclopropanecarbonitriles

Structure

Formed by the substitution of a hydrogen atom in the cyclopropanecarbonitrile molecule with a 4-iodophenyl group

Key features

Characterized by its cyclopropane ring and nitrile functional group

Versatility

Acts as a versatile building block for the synthesis of various organic compounds

Applications

Used as a starting material for the preparation of pharmaceuticals, agrochemicals, and materials for industrial applications

Unique properties

Exhibits unique structural and chemical properties due to its 4-iodophenyl group

Functionalization

The 4-iodophenyl group allows for easy functionalization, making it a valuable tool in organic synthesis

Reactivity

The nitrile functional group can participate in various chemical reactions, such as nucleophilic addition, hydrolysis, and reduction

Stability

The cyclopropane ring is a strained three-membered ring, which can influence the compound's reactivity and stability

Hazards

Due to the presence of the iodine atom, it may have potential hazards related to its reactivity, toxicity, or environmental impact, and should be handled with care in a laboratory setting.

Check Digit Verification of cas no

The CAS Registry Mumber 124276-79-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,2,7 and 6 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 124276-79:
(8*1)+(7*2)+(6*4)+(5*2)+(4*7)+(3*6)+(2*7)+(1*9)=125
125 % 10 = 5
So 124276-79-5 is a valid CAS Registry Number.

124276-79-5Relevant articles and documents

Nickel-Catalyzed Favorskii-Type Rearrangement of Cyclobutanone Oxime Esters to Cyclopropanecarbonitriles

Shuai, Bin,Fang, Ping,Mei, Tian-Sheng

, p. 1637 - 1641 (2021/10/02)

A nickel-catalyzed base-promoted rearrangement of cyclobutanone oxime esters to cyclopropanecarbonitriles was developed. The ring opening of cyclobutanone oxime esters occurs at the sterically less hindered side. A base-promoted nickelacyclobutane intermediate, formed in situ, is assumed to be involved in the formation of the product.

CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES

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Page/Page column 99-100; 101, (2021/07/02)

The invention relates to compounds of formula (I) and to their use in treating or preventing an inflammatory disease or a disease associated with an undesirable immune response: (I) wherein, RA1, RA2, RC and RD are as defined herein.

The diastereoselective synthesis of 2,3-diaryl-3-cyano-substituted pyrrolidines via the MgI2 mediated ring expansion of aryl cyclopropyl nitriles

Stead, Darren

supporting information, (2020/09/04)

The MgI2 mediated reaction of aryl substituted cyclopropyl nitriles with tosyl aldimines to give 2,3-diaryl-3-cyano-substituted pyrrolidines has been demonstrated. In all cases, the trans-diastereoisomer was determined to be the major product.

LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS

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Paragraph 0607, (2013/03/26)

Compounds, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat, prevent or diagnose diseases, disorders, or conditions associated with one or more of the lysophosphatidic acid receptors are provided.

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