1-(4-Iodophenyl)cyclopropanecarbonitrile

Base Information

Chemical Name:1-(4-Iodophenyl)cyclopropanecarbonitrile
CAS No.:124276-79-5
Molecular Formula:C₁₀H₈IN
Molecular Weight:269.085
Hs Code.:
DSSTox Substance ID:DTXSID101276110
Mol file:124276-79-5.mol

Synonyms:1-(4-IODOPHENYL)CYCLOPROPANECARBONITRILE;124276-79-5;1-(4-iodophenyl)cyclopropane-1-carbonitrile;MFCD11036668;SCHEMBL10529133;NYALZYNMNOTLSH-UHFFFAOYSA-N;DTXSID101276110;AKOS027254227;DA-13776;SY226747;CS-0334793;A926022

Suppliers and Price of 1-(4-Iodophenyl)cyclopropanecarbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-(4-Iodophenyl)cyclopropanecarbonitrile
1g
$ 549.00

Crysdot
1-(4-Iodophenyl)cyclopropanecarbonitrile 95+%
1g
$ 428.00

Chemenu
1-(4-Iodophenyl)cyclopropanecarbonitrile 95%
1g
$ 404.00

Atlantic Research Chemicals
1-(4-Iodophenyl)cyclopropanecarbonitrile 95%
250mgs:
$ 144.92

Alichem
1-(4-Iodophenyl)cyclopropanecarbonitrile
1g
$ 477.75

Alichem
1-(4-Iodophenyl)cyclopropanecarbonitrile
250mg
$ 178.36

AK Scientific
1-(4-Iodophenyl)cyclopropanecarbonitrile
1g
$ 998.00

Total 6 raw suppliers

Chemical Property of 1-(4-Iodophenyl)cyclopropanecarbonitrile

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:268.97015
Heavy Atom Count:12
Complexity:215

Purity/Quality:

99%, ^*data from raw suppliers

1-(4-Iodophenyl)cyclopropanecarbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC1(C#N)C2=CC=C(C=C2)I

Technology Process of 1-(4-Iodophenyl)cyclopropanecarbonitrile

There total 6 articles about 1-(4-Iodophenyl)cyclopropanecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: (Z)-2-(4-iodophenyl)cyclobutan-1-one O-(4-(trifluoromethyl)benzoyl)oxime

: 124276-79-5
1-(4-iodophenyl)cyclopropane-1-carbonitrile

Guidance literature:: (Z)-2-(4-iodophenyl)cyclobutan-1-one O-(4-(trifluoromethyl)benzoyl)oxime; With (1,2-dimethoxyethane)dichloronickel(II); 4,4'-di-tert-butyl-2,2'-bipyridine; In N,N-dimethyl-formamide; at 20 ℃; for 0.25h; Glovebox;

With lithium hexamethyldisilazane; In N,N-dimethyl-formamide; at 20 ℃; for 12h;
DOI:10.1055/s-0039-1690872

Reference yield: 61.0%

: 51628-12-7
4-iodophenylacetonitrile

: 107-04-0
1-Bromo-2-chloroethane

: 124276-79-5
1-(4-iodophenyl)cyclopropane-1-carbonitrile

Guidance literature:: With N-benzyl-N,N,N-triethylammonium chloride; sodium hydroxide; at 60 ℃;

Reference yield:

: 1-(cyclopropylidenemethyl)-4-iodobenzene

: 124276-79-5
1-(4-iodophenyl)cyclopropane-1-carbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1 h / 0 °C

1.2: 1 h / 75 °C

2.1: triethylamine / dichloromethane / 1 h / 0 - 20 °C

3.1: (1,2-dimethoxyethane)dichloronickel(II); 4,4'-di-tert-butyl-2,2'-bipyridine / N,N-dimethyl-formamide / 0.25 h / 20 °C / Glovebox

3.2: 12 h / 20 °C

With (1,2-dimethoxyethane)dichloronickel(II); triethylamine; 3-chloro-benzenecarboperoxoic acid; 4,4'-di-tert-butyl-2,2'-bipyridine; In dichloromethane; N,N-dimethyl-formamide; 3.1: |Favorskii Rearrangement / 3.2: |Favorskii Rearrangement;
DOI:10.1055/s-0039-1690872