124421-36-9Relevant articles and documents
Amino acid derivative anticonvulsant
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, (2008/06/13)
The present invention relates to compounds of the formula STR1
Amino acid derivative anticonvulsant
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, (2008/06/13)
The present invention relates to compounds exhibiting central nervous system (CNS) activity which are useful in the treatment of epilepsy and other CNS disorders. The compounds of this invention have the following general formula: STR1 and pharmaceutically acceptable salts thereof.
Preparation and Anticonvulsant Activity of a Series of Functionalized α-Aromatic and α-Heteroaromatic Amino Acids
Kohn, Harold,Sawhney, Kailash N.,LeGall, Philippe,Conley, Judith D.,Robertson, David W.,Leander, J. David
, p. 919 - 926 (2007/10/02)
We recently reported the potent anticonvulsant activity of (R,S)-α-acetamido-N-benzyl-α-phenylacetamide (2b).Selectively substituted derivatives of this compound have now been prepared (23 examples) and evaluated in the maximal electroshock seizure (MES)