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3-Boc-6-Amino-3-azabicyclo[3.2.0]heptane is a bicyclic chemical compound with the molecular formula C11H19NO2. It is a derivative of azabicyclo[3.2.0]heptane, featuring a nitrogen-containing ring. 3-Boc-6-aMino-3-azabicyclo[3.2.0]heptane is characterized by the presence of an amino group and a tert-butoxycarbonyl (Boc) protecting group at the third and sixth positions of the azabicyclo[3.2.0]heptane ring, respectively. This unique structure and functional groups make it a valuable building block in organic synthesis for the preparation of pharmaceuticals and other biologically active molecules.

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  • 1250884-66-2 Structure
  • Basic information

    1. Product Name: 3-Boc-6-aMino-3-azabicyclo[3.2.0]heptane
    2. Synonyms: 3-Boc-6-aMino-3-azabicyclo[3.2.0]heptane;tert-Butyl (1S,5R)-6-amino-3-azabicyclo[3.2.0]heptane-3-carboxylate;(1R,5S)-rel-tert-Butyl 6-amino-3-azabicyclo[3.2.0]heptane-3-carboxylate;tert-Butyl (1S,5R)-6-amino-3-azabicyclo[3.2.0]heptane-3-carboxylate - B6578;tert-butyl cis-6-amino-3-azabicyclo[3.2.0]heptane-3-carboxylate
    3. CAS NO:1250884-66-2
    4. Molecular Formula: C11H20N2O2
    5. Molecular Weight: 212.2887
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1250884-66-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 294.8±23.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.111±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 10.47±0.20(Predicted)
    10. CAS DataBase Reference: 3-Boc-6-aMino-3-azabicyclo[3.2.0]heptane(CAS DataBase Reference)
    11. NIST Chemistry Reference: 3-Boc-6-aMino-3-azabicyclo[3.2.0]heptane(1250884-66-2)
    12. EPA Substance Registry System: 3-Boc-6-aMino-3-azabicyclo[3.2.0]heptane(1250884-66-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1250884-66-2(Hazardous Substances Data)

1250884-66-2 Usage

Uses

Used in Pharmaceutical Industry:
3-Boc-6-Amino-3-azabicyclo[3.2.0]heptane is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and functional groups allow for the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, 3-Boc-6-Amino-3-azabicyclo[3.2.0]heptane serves as a versatile building block for the preparation of a wide range of biologically active molecules. Its amino and Boc protecting group enable various chemical reactions, facilitating the synthesis of complex organic compounds.
Used in Research and Development:
3-Boc-6-Amino-3-azabicyclo[3.2.0]heptane is utilized in research and development for the exploration of new chemical reactions and the discovery of novel biologically active molecules. Its unique structure and functional groups provide opportunities for innovative synthetic strategies and the development of new chemical entities with potential applications in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 1250884-66-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,0,8,8 and 4 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1250884-66:
(9*1)+(8*2)+(7*5)+(6*0)+(5*8)+(4*8)+(3*4)+(2*6)+(1*6)=162
162 % 10 = 2
So 1250884-66-2 is a valid CAS Registry Number.

1250884-66-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 6-amino-3-azabicyclo[3.2.0]heptane-3-carboxylate

1.2 Other means of identification

Product number -
Other names 3-BOC-6-AMINO-3-AZABICYCLO[3.2.0]HEPTANE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1250884-66-2 SDS

1250884-66-2Downstream Products

1250884-66-2Relevant articles and documents

Photocycloaddition of N-Benzylmaleimide to Alkenes As an Approach to Functional 3-Azabicyclo[3.2.0]heptanes

Skalenko, Yevhen A.,Druzhenko, Tetiana V.,Denisenko, Aleksandr V.,Samoilenko, Maryna V.,Dacenko, Oleksandr P.,Trofymchuk, Serhii A.,Grygorenko, Oleksandr O.,Tolmachev, Andrey A.,Mykhailiuk, Pavel K.

, p. 6275 - 6289 (2018)

A one-step synthesis of functionalized 3-azabicyclo[3.2.0]heptanes by [2+2]-photochemical intermolecular cycloaddition of N-benzylmaleimide to alkenes was elaborated. The obtained compounds were easily transformed into the bi- and tricyclic analogues of piperidine, morpholine, piperazine, and GABA, which are advanced building blocks for drug discovery.

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