125225-63-0

Basic information

• Product Name: 25(S)-Ruscogenin 1-O-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranoside
• Synonyms: 25(S)-Ruscogenin 1-O-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranoside;(1beta,3beta,25S)-3-Hydroxyspirost-5-en-1-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-xylopyranoside;(25S)-ruscogenin 1-O-alpha-L-rhamnopyranosyl(1->2)-beta-D-xylopyranoside
• CAS NO: 125225-63-0
• Molecular Formula: C₃₈H₆₀O₁₂
• Molecular Weight: 708.88
• Mol File: 125225-63-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 25(S)-Ruscogenin 1-O-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: 25(S)-Ruscogenin 1-O-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranoside(125225-63-0)
• EPA Substance Registry System: 25(S)-Ruscogenin 1-O-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranoside(125225-63-0)

Safety Data

• Hazardous Substances Data: 125225-63-0(Hazardous Substances Data)

Usage

Uses

Used in Herbal Medicine:
25(S)-Ruscogenin 1-O-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranoside is used as a therapeutic agent for treating conditions such as chronic venous insufficiency and hemorrhoids. It is valued for its ability to improve blood circulation, reduce swelling, and provide relief from symptoms associated with these conditions.
Used in Anticancer Applications:
25(S)-Ruscogenin 1-O-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranoside is used as an anticancer agent, demonstrating its potential to inhibit the growth of cancer cells. Its potent anti-inflammatory and antioxidant properties contribute to its effectiveness in this application.
Used in Cardiovascular Disease Treatment:
25(S)-Ruscogenin 1-O-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranoside is used as a therapeutic agent in the treatment of cardiovascular diseases. Its ability to improve blood circulation and reduce inflammation makes it a promising candidate for further research and development in this field.
Used in Skin Disorder Treatment:
25(S)-Ruscogenin 1-O-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranoside is used as a therapeutic agent for the treatment of skin disorders. Its anti-inflammatory and antioxidant properties are beneficial in managing symptoms and promoting skin health.
Overall, 25(S)-Ruscogenin 1-O-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranoside has shown promising therapeutic effects across various medical applications and has the potential for further research and development in the field of medicine.

Upstream product

• 88623-84-1 (25R)-ruscogenin 1-O-α-L-rhamnopyranosyl-(1->2)-4-O-sulfo-β-D-arabinopyranoside 

Downstream Products

• 87-72-9 D-Xylose 
• 73-34-7 L-rhamnose 
• 472-11-7 25(S)-ruscogenin 
• 6155-50-6 25(S)-ruscogenin 1,3-diacetate 

Relevant articles and documents

Comparative Studies on the Constituents of Ophiopogonis Tuber and Its Congeners. III. Studies on the Constituents of the Subterranean Part of Ophiopogon ohwii Okuyama and O. jaburan (Kunth) Lodd.

Six steroidal glycosides tentatively named glycosides O-1, O-2 (1), O-3 (2), O-4 (3), O-5 (4) and O-6 (5), were isolated from the subterranean part of Ophiopogon ohwii Okuyama (Liliaceae) and another six steroidal glycosides, tentatively named glycosides J-1, J-2 (6), J-3 (7), J-4 (8), J-5 (9) and J-6 (10), were isolated from the subterranean part of O. jaburan (Kunth) Lodd.Glycosides O-1 and J-1 were identified as so-called β-sitosterol β-D-glucopyranoside.The structures of 1-10 were established as ophiopogonin B (1), Ophiopogonin D (2), ruscogenin 1-O-α-L-rhamnopyranosyl(1->2)-4-O-sulfo-β-D-fucopyranoside (3), ruscogenin 1-O-α-L-rhamnopyranosyl(1->2)-4-O-sulfo-α-L-arabinopyranoside (=glycoside E of O. planiscapus Nakai) (4), 26-O-β-D-glucopyranosyl 22-hydroxy-25(R)-furost-5-en-1β,3β,26-triol 1-O-α-L-rhamnopyranosyl(1->2)-4-O-sulfo-β-D-fucopyranoside (5), ophiopogonin D (=glycoside O-3 (2)) (6), a mixture of 1-O-α-L-rhamnopyranosyl(1->2)-4-O-sulfo-β-D-fucopyranosido-3-O-β-D-glucopyranosides of ruscogenin and neoruscogenin (7), neoruscogenin 1-O-α-L-rhamnopyranosyl(1->2)-4-O-sulfo-α-L-arabinopyranosido-3-O-β-D-glucopyranoside (8), a mixture of 26-O-β-D-glucopyranosyl 22-hydroxy-25(R)-furost-5-en-1β,3β,26-triol 1-O-α-L-rhamnopyranosyl(1->2)-4-O-sulfo-β-D-fucopyranosido-3-O-β-D-glucopyranoside and 26-O-β-D-glucopyranosyl 22-hydroxyfurost-5,25(27)-dien-1β,3β,26-triol 1-O-α-L-rhamnopyranosyl(1->2)-4-O-sulfo-β-D-fucopyranosido-3-O-β-D-glucopyranoside (9), and 26-O-β-D-glucopyranosyl 22-hydroxyfurost-5,25(27)-dien-1β,3β,26-triol 1-O-α-L-rhamnopyranosyl(1->2)-4-O-sulfo-α-L-arabinopyranosido-3-O-β-d-glucopyranoside (10).It is interesting that the main saponins, ophiopogonins B and D, found in Ophiopogonis Tuber (obtained from O. japonicus Ker-Gawler) were also found in O. ohwii (Okuyama and the latter saponin was also found in O. jaburan (Kunth) Lodd.Further, several steroidal glycosides carrying sulfate on the sugar moiety were found in Liliaceous plants belonging to the genus Ophiopogon. Keywords - Ophiopogonis Tuber; Ophiopogon ohwii; Ophiopogon jaburan; Liliaceae; spirostanol glycoside; furostanol glycoside; sulfated steroidal glycoside

Comparative Studies on the Constituents of Ophiopogonis Tuber and Its Congeners. II. Studies on the Constituents of the Subterranean Part of Ophiopogon planiscapus NAKAI. (1)

Seven steroidal glycosides, tentatively named glycosides A, B(1), C(2), D(3), E(4), F(5), and G(6), were isolated from the methanol extract of the subterranean part of Ophiopogon planiscapus NAKAI (Liliaceae).The structures of these glycosides were established as so-called β-sitosterol-β-D-glucopyranoside, diosgenin 3-O-α-L-rhamnopyranosyl(12)-β-D-glucopyranoside (=prosapogenin A of dioscin) (1), diosgenin 3-O-2)>-4)>-β-D-glucopyranoside (=deltonin) (2), 26-O-β-D-gucopyranosyl-22-hydroxyfurost-5-ene-3β,26-diol 3-O-α-L-rhamnopyranosyl(12)-β-D-glucopyranoside (3), ruscogenin 1-O-α-L-rhamnopyranosyl(12)-4-O-sulfo-α-L-arabinopyranoside (4), 26-O-β-D-glucopyranosyl-22-hydroxyfurost-5-ene-3β,26-diol 3-O-2)>-4)>-β-D-glucopyranoside (=22-hydroxyl form of deltoside) (5) and 26-O-β-D-glucopyranosyl-22-hydroxyfurost-5-ene-1β,3β,26-triol 1-O-α-L-rhamnopyranosyl(12)-4-O-sulfo-α-L-arabinopyranosides (6), respectively.The relationship of steroidal glycosides of Ophiopogon japonicus KER-GAWLER, O. planiscapus NAKAI and Liriope platyphylla WANG et TANG, which are considered to be the plants of origin of the crude drug, Ophiopogonis Tuber, is also discussed.This is believed to be the first report of steroidal glycosides having a sulfate group on the sugar moiety.Keywords - Ophiopogonis Tuber; Ophiopogon planiscapus; Liliaceae; spirostanol glycoside; furostanol glycoside; sulfated steroidal glycoside; diosgenin; ruscogenin