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CAS

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125290-60-0

1-(2,4-difluorophenyl)-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 125290-60-0 Structure

  • Basic information

    1. Product Name: 1-(2,4-difluorophenyl)-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
    2. Synonyms: 1-(2,4-Difluorophenyl)-6-fluoro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
    3. CAS NO:125290-60-0
    4. Molecular Formula: C22H20F3N3O3
    5. Molecular Weight: 431.4077
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 125290-60-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 641.2°C at 760 mmHg
    3. Flash Point: 341.6°C
    4. Appearance: N/A
    5. Density: 1.397g/cm3
    6. Vapor Pressure: 2.55E-17mmHg at 25°C
    7. Refractive Index: 1.598
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 1-(2,4-difluorophenyl)-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1-(2,4-difluorophenyl)-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(125290-60-0)
    12. EPA Substance Registry System: 1-(2,4-difluorophenyl)-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(125290-60-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 125290-60-0(Hazardous Substances Data)

125290-60-0 Usage

Type of Drug

Synthetic 4th generation fluoroquinolone antibiotic

Mechanism of Action

Inhibits bacterial DNA replication and protein synthesis by inhibiting bacterial topoisomerase IV and DNA gyrase

Effective Against

Wide range of gram-positive and gram-negative bacteria, including those resistant to other antibiotics

Indications

Respiratory tract infections, skin and soft tissue infections, and urinary tract infections

Forms Available

Tablet and liquid forms

Side Effects

Nausea, diarrhea, and dizziness

Drug Group

Fluoroquinolones

Usage

Treats various bacterial infections

Tolerance

Generally well-tolerated

Resistance

Effective against bacteria resistant to other antibiotics

Prescription

Typically prescribed by healthcare professionals for serious infections

Check Digit Verification of cas no

The CAS Registry Mumber 125290-60-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,2,9 and 0 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 125290-60:
(8*1)+(7*2)+(6*5)+(5*2)+(4*9)+(3*0)+(2*6)+(1*0)=110
110 % 10 = 0
So 125290-60-0 is a valid CAS Registry Number.

125290-60-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2,4-difluorophenyl)-6-fluoro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid

1.2 Other means of identification

Product number -
Other names 3-Quinolinecarboxylicacid,1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-5-methyl-7-(3-methyl-1-piperazinyl)-4-oxo

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:125290-60-0 SDS

125290-60-0Downstream Products

125290-60-0Relevant articles and documents

Synthesis and Biological Activity of 5-Alkyl-1,7,8-trisubstituted-6-fluoroquinoline-3-carboxylic Acids

Hagen, Susan E.,Domagala, Johan M.,Heifetz, Carl L.,Johnson, Judith

, p. 1155 - 1161 (2007/10/02)

A series of 5-alkyl-1,7,8-trisubstituted-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids was prepared and evaluated for in vitro and in vivo antibacterial activity.When compared to the 5-hydrogen analogues, the presence of the 5-methyl group enhanc

Antibacterial agents

-

, (2008/06/13)

Novel naphthyridine-, and quinolinecarboxylic acids as antibacterial agents are described as well as methods for their manufacture, formulation, and use in treating bacterial infections including the description of certain novel intermediates used in the

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