125483-56-9

Basic information

• Product Name: Cyclobutanecarboxylic acid, 1-amino-, phenylmethyl ester (9CI)
• Synonyms: Cyclobutanecarboxylic acid, 1-amino-, phenylmethyl ester (9CI);Cyclobutanecarboxylic acid, 1-aMino-, phenylMethyl ester
• CAS NO: 125483-56-9
• Molecular Formula: C₁₂H₁₅NO₂
• Molecular Weight: 205.253
• Product Categories: AMINOACID
• Mol File: 125483-56-9.mol

Chemical Properties

• Boiling Point: 302.6±25.0 °C(Predicted)
• Appearance: /
• Density: 1.170±0.06 g/cm3(Predicted)
• PKA: 8.05±0.20(Predicted)
• CAS DataBase Reference: Cyclobutanecarboxylic acid, 1-amino-, phenylmethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclobutanecarboxylic acid, 1-amino-, phenylmethyl ester (9CI)(125483-56-9)
• EPA Substance Registry System: Cyclobutanecarboxylic acid, 1-amino-, phenylmethyl ester (9CI)(125483-56-9)

Safety Data

• Hazardous Substances Data: 125483-56-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Chemistry:
Cyclobutanecarboxylic acid, 1-amino-, phenylmethyl ester (9CI) is used as a synthetic intermediate for the development of various organic compounds. Its unique structure allows for versatile chemical reactions, making it a valuable building block in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
Cyclobutanecarboxylic acid, 1-amino-, phenylmethyl ester (9CI) is used as a potential drug candidate in the pharmaceutical industry. Its unique structure and functional groups may offer new opportunities for the development of novel therapeutic agents, particularly in the areas of medicinal chemistry and drug design.
Used in Biotechnology Industry:
Cyclobutanecarboxylic acid, 1-amino-, phenylmethyl ester (9CI) is used as a component in biotechnological applications. Its potential use in the development of new bioactive molecules, as well as its possible role in the study of biological processes, makes it an interesting compound for further exploration in the biotechnology field.

Upstream product

• 3049-40-9 7-oxa-5-aza-spiro[3.4]octane-6,8-dione 
• 100-51-6 benzyl alcohol 
• 1164340-01-5 benzyl 1-(tert-butoxycarbonylamino)cyclobutanecarboxylate 
• 120728-10-1 1-[(tert-butoxycarbonyl)amino]cyclobutanecarboxylic acid 
• 100-39-0 benzyl bromide 

Downstream Products

• 1164340-05-9 4-[(S)-2-({5-[(1-benzyloxycarbonylcyclobutyl)carbamoylmethoxy]-1-phenyl-1H-pyrazole-3-carbonyl}amino)-4-tert-butoxycarbonylbutyryl]piperazine-1-carboxylic acid ethyl ester 
• 1413936-70-5 benzyl 1-((((3R)-1-aza-6-(2,3-dihydro-2,2,4,6,7-pentamethyl-2H-1-benzofuran-5-yl)sulfonyl)guanidino)-3-(9H-9-fluorenylmethoxycarbonylamido)-2-oxohexanyl)cyclobutanecarboxylate 

Relevant articles and documents

Binaphthyl-anchored antibacterial tripeptide derivatives with hydrophobic C-terminal amino acid variations

The facile synthesis of seven new dicationic tripeptide benzyl ester derivatives, with hydrophobic group variations in the C-terminal amino acid component, is described. Moderate to good activity was seen against Gram-positive bacteria in vitro. One cyclohexylsubstituted compound 2c was tested more widely and showed good potency (MIC values ranging from 2-4 μg/mL) against antibiotic-resistant strains of Staphylococcus aureus and Enterococci (VRE, VSE), and against Staphylococcus epidermidis.

PYRAZOLE-CARBOXAMIDE DERIVATIVES AS P2Y12 ANTAGONISTS

The present invention relates to compounds of the Formula (I), wherein R1; R2; Z; A; B; D; Q; J; V; G and M have the meanings indicated in the claims. The compounds of the formula I are valuable pharmacologically active compounds. They exhibit a strong anti-aggregating effect on platelets and thus an anti-thrombotic effect and are suitable e.g. for the therapy and prophylaxis of cardio-vascular disorders like thromboembolic diseases or restenoses. They are reversible antagonists of the platelet ADP receptor P2Y12, and can in general be applied in conditions in which an undesired activation of the platelet ADP receptor P2Y12 is present or for the cure or prevention of which an inhibition of the platelet ADP receptor P2Y12 is intended. The invention furthermore relates to processes for the preparation of compounds of the Formula (I), their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.

1-CARBAMOYLCYCLOALKYLCARBOXYLIC ACID COMPOUNDS, PROCESSES FRO MAKING AND USES THEREOF

The invention relates to the field of pharmaceutics and more specifically to novel cycloalkylamidoacid compositions useful in the preparation of cycloalkyaminoacids and oxazolidinediones, and processes for making cycloamidoacids. Formula (1)