- Palladium-catalyzed cross-coupling reaction of azides with isocyanides
-
An efficient palladium-catalyzed cross-coupling reaction of azides with isocyanides is developed, providing a general synthetic route to unsymmetric carbodiimides with excellent yields. This method shows a broad substrate scope, including not only aryl azides, but also unactivated benzyl and alkyl azides. Furthermore, from readily available substrates, Pd-catalyzed coupling with a tandem amine insertion cascade to obtain unsymmetric trisubstituted guanidines has been achieved in a one-pot fashion.
- Zhang, Zhen,Li, Zongyang,Fu, Bin,Zhang, Zhenhua
-
supporting information
p. 16312 - 16315
(2015/11/16)
-
- Synthesis of carbodiimides by I2/CHP-mediated cross-coupling reaction of isocyanides with amines under metal-free conditions
-
An I2/CHP-mediated cross-coupling reaction of isocyanides with readily accessible amines via C-N formation is described for carbodiimide synthesis in moderate to excellent yields. This represents a metal-free strategy for a coupling reaction of isocyanides with amines, and it provides an efficient approach for symmetric and unsymmetric functionalized carbodiimide derivative synthesis under mild conditions.
- Zhu, Tong-Hao,Wang, Shun-Yi,Tao, Yang-Qing,Ji, Shun-Jun
-
supporting information
p. 1974 - 1977
(2015/04/27)
-
- The efficient synthesis of carbodiimides using a titanium imido complex
-
An efficient rt synthesis of carbodiimides or ureas from the combination of a titanium imido complex 2 and a range of 12 aryl and aliphatic isocyanates is described. Control experiments suggest that carbodimide formation is via heterocumulene metathesis t
- Anderson, James C.,Bou-Moreno, Rafael
-
experimental part
p. 9182 - 9186
(2011/01/12)
-