1258940-00-9 Usage
Uses
Used in Pharmaceutical Industry:
(S)-3-PHENYL PIPERIDINE is used as a chiral intermediate for the synthesis of various pharmaceutical compounds, including analgesics and antipsychotic medications. Its chiral nature allows for the production of enantiopure drugs, which can have different therapeutic effects and reduce potential side effects.
Used in Organic Synthesis:
(S)-3-PHENYL PIPERIDINE is used as a building block in organic synthesis for the creation of diverse chemical compounds. Its versatile structure enables the development of new molecules with potential applications in various fields, such as materials science, agrochemicals, and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 1258940-00-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,8,9,4 and 0 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1258940-00:
(9*1)+(8*2)+(7*5)+(6*8)+(5*9)+(4*4)+(3*0)+(2*0)+(1*0)=169
169 % 10 = 9
So 1258940-00-9 is a valid CAS Registry Number.
1258940-00-9Relevant articles and documents
Asymmetric synthesis of chiral N-sulfinyl 3-alkyl- and 3-arylpiperidines by α-alkylation of N-sulfinyl imidates with 1-chloro-3-iodopropane
Colpaert, Filip,Mangelinckx, Sven,De Kimpe, Norbert
, p. 234 - 244 (2011/03/19)
α-Alkylation of N-sulfinyl imidates with 1-chloro-3-iodopropane successfully led to 2-substituted N-tert-butanesulfinyl-5-chloropentanimidates in acceptable diastereomeric ratios (dr 67/33 to 72/28) and good yields (74-86%). Subsequent reduction with NaBH4 led to the corresponding 2-substituted N-tert-butanesulfinyl-5-chloropentylamines, which could be cyclized to a range of new chiral 3-substituted N-tert-butanesulfinylpiperidines using NaH in DMSO. Finally, the N-tert-butanesulfinylpiperidines could be efficiently deprotected to enantiomerically pure 3-alkyl- and 3-arylpiperidine hydrochlorides.
