Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1261645-01-5

2-bromo-6-methoxybenzoyl chloride is an organic chemical compound that serves as an intermediate in the synthesis of various organic compounds.
Used in Pharmaceutical Industry:
2-bromo-6-methoxybenzoyl chloride is used as a chemical intermediate for the synthesis of Fluoren-1-ol (F462450), a metabolite of the polycyclic aromatic hydrocarbon (PAH) micropollutant Fluorene (F462002). This metabolite has potential mutagenic effects and is utilized as a biomarker to assess exposure to PAHs and environmental tobacco smoke in the general population.

1261645-01-5 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 1261645-01-5 Structure

  • Basic information

    1. Product Name: 2-broMo-6-Methoxybenzoyl chloride
    2. Synonyms: 2-broMo-6-Methoxybenzoyl chloride
    3. CAS NO:1261645-01-5
    4. Molecular Formula: C8H6BrClO2
    5. Molecular Weight: 249.48904
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1261645-01-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-broMo-6-Methoxybenzoyl chloride(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-broMo-6-Methoxybenzoyl chloride(1261645-01-5)
    11. EPA Substance Registry System: 2-broMo-6-Methoxybenzoyl chloride(1261645-01-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1261645-01-5(Hazardous Substances Data)

1261645-01-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1261645-01-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,1,6,4 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1261645-01:
(9*1)+(8*2)+(7*6)+(6*1)+(5*6)+(4*4)+(3*5)+(2*0)+(1*1)=135
135 % 10 = 5
So 1261645-01-5 is a valid CAS Registry Number.

1261645-01-5Downstream Products

1261645-01-5Relevant articles and documents

A general route for 13C-labeled fluorenols and phenanthrenols via palladium-catalyzed cross-coupling and one-carbon homologation

Wu, Ruilian,Silks,Olivault-Shiflett, Morgane,Williams, Robert F.,Ortiz, Erick G.,Stotter, Philip,Kimball, David B.,Martinez, Rodolfo A.

, p. 581 - 586 (2013)

A series of 13C-labeled polyaromatic hydrocarbons (PAHs), fluorenols and phenanthrenols were synthesized from commercially available 13C-labeled starting material giving rise to M + 6 isotopomers. This was accomplished using key pall

Synthesis of Methoxy-, Methylenedioxy-, Hydroxy-, and Halo-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Inhibitors and Their Biological Activity for Drug-Resistant Cancer

Hu, De-Xuan,Tang, Wen-Lin,Zhang, Yu,Yang, Hao,Wang, Wenjie,Agama, Keli,Pommier, Yves,An, Lin-Kun

, p. 7617 - 7629 (2021/06/25)

As a recently discovered DNA repair enzyme, tyrosyl-DNA phosphodiesterase 1 (TDP1) removes topoisomerase IB (TOP1)-mediated DNA protein cross-links. Inhibiting TDP1 can potentiate the cytotoxicity of TOP1 inhibitors and overcome cancer cell resistance to

HISTONE ACETYLTRANSFERASE MODULATORS AND COMPOSITIONS AND USES THEREOF

-

Paragraph 0161, (2020/08/22)

Compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.

Palladium-Catalyzed Stereoselective Aza-Wacker-Heck Cyclization: One-Pot Stepwise Strategy toward Tetracyclic Fused Heterocycles

Chen, Li-Yuan,Chuang, Ta-Hsien,Lai, Chin-Hung,Tang, Rong-Shiow

supporting information, p. 9337 - 9341 (2020/12/21)

Palladium-catalyzed intramolecular tandem cyclization reactions were conducted for the synthesis of densely cis/cis-fused aza-tetracyclic structures. The process involved a palladium(II)-catalyzed aerobic aza-Wacker reaction, followed by a palladium(0)-catalyzed Heck reaction. The effects of the solvent and benzene substitution pattern on the one-pot, two-step cascade reaction were studied systematically, and a probable mechanism was proposed. Strained pentahydrobenzo[f]cyclopenta[hi]indolizin-6-one and racemic γ-lycorane can also be synthesized rapidly using this palladium-catalyzed aza-Wacker-Heck cyclization reaction.

Palladium-catalyzed intramolecular C-H arylation of 2-halo-: N -Boc- N -arylbenzamides for the synthesis of N-H phenanthridinones

Hu, Quan-Fang,Gao, Tian-Tao,Shi, Yao-Jie,Lei, Qian,Yu, Luo-Ting

, p. 13879 - 13890 (2018/04/25)

A palladium catalyzed synthesis of N-H phenanthridinones was developed via C-H arylation. The protocol gives phenanthridinones regioselectively by one-pot reaction without deprotection. It exhibits broad substrate scope and affords targets in up to 95% yields. Importantly, it could be applied for the less reactive o-chlorobenzamides.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1261645-01-5