1262411-34-6

Basic information

• Product Name: 4-methylthiane-4-carboxylic acid
• Synonyms: 4-methylthiane-4-carboxylic acid;4-Methyl-tetrahydro-thiopyran-4-carboxylic acid
• CAS NO: 1262411-34-6
• Molecular Formula: C7H12O2S
• Molecular Weight: 160.24
• Mol File: 1262411-34-6.mol

Chemical Properties

• Boiling Point: 292.7±33.0 °C(Predicted)
• Appearance: /
• Density: 1.172±0.06 g/cm3(Predicted)
• PKA: 4.60±0.20(Predicted)
• CAS DataBase Reference: 4-methylthiane-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methylthiane-4-carboxylic acid(1262411-34-6)
• EPA Substance Registry System: 4-methylthiane-4-carboxylic acid(1262411-34-6)

Safety Data

• Hazardous Substances Data: 1262411-34-6(Hazardous Substances Data)

Upstream product

• 128094-82-6 tetrahydro-thiopyran-4-carboxylic acid methyl ester 
• 195503-40-3 tetrahydro-2H-thiopyrane-4-carbonitrile 

Relevant articles and documents

TRICYCLIC SULFONES AS ROR GAMMA MODULATORS

There are described RORγ modulators of the formula (I), and formula (II) or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORγ activity, for example, autoimmune and/or inflammatory disorders.

TRICYCLIC COMPOUND AND USE THEREOF

The present invention relates to: a compound selected from the group consisting of a tricyclic compound having the structure of formula I, a pharmaceutically acceptable salt, an isomer, a solvate and a precursor thereof; and a use thereof. The compound effectively controls GPR40, and thus, can be effectively used for the prophylaxis or treatment of diseases associated with GPR40, for example, diabetes and many other diseases.