1266399-53-4

Basic information

• Product Name: C₁₉H₂₁N₃O₅
• Synonyms: C₁₉H₂₁N₃O₅
• CAS NO: 1266399-53-4
• Molecular Weight: 371.393
• Mol File: 1266399-53-4.mol

Chemical Properties

• CAS DataBase Reference: C₁₉H₂₁N₃O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₂₁N₃O₅(1266399-53-4)
• EPA Substance Registry System: C₁₉H₂₁N₃O₅(1266399-53-4)

Safety Data

• Hazardous Substances Data: 1266399-53-4(Hazardous Substances Data)

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 10493-06-8 3-(3,4-dimethoxyphenyl)-1-(2-hydroxy-4-methoxyphenyl)-2-propen-1-one 
• 10493-09-1 7,3',4'-trimethoxyflavanone 
• 563-41-7 semicarbazide hydrochloride 
• 552-41-0 1-(2-hydroxy-4-methoxyphenyl)ethanone 

Downstream Products

• 1266399-43-2 4-(3,4-dimethoxyphenyl)-7-methoxy-4H-benzopyran[4,3-d][1,2,3]selenadiazole 

Relevant articles and documents

Synthesis and cytotoxic activity of 4-aryl-4H-chromeno[4,3-d] [1,2,3] selenadiazoles

Fourteen 4-Aryl-4H-chromeno[4,3-d][1,2,3] selenadiazole derivatives were synthesized by the reaction of fla-vonone-4-semicarbazones with SeO2. The structures of the target compounds 1a-n were elucidated by 1H NMR, IR spectra, ESI-MS and elemental analyses. The preliminary cytotoxic activities of 1a-n against K562, KB, A549, SMC-7721 and SGC-7901 cell lines were evaluated by MTT method, indicating that most compounds displayed moderate to good antiproliferative activities against K562 and KB cell lines. Compounds 1m and 1n, the most potent ones, were promising template for development of novel potent antitumor agents.