Synthesis and evaluation of 1,2,4-methyltriazines as mGluR5 antagonists
In previous studies we showed that 3-(substituted phenylethynyl)-5- methyl[1,2,4]triazine analogues of MPEP were potent antagonists of glutamate-mediated mobilization of internal calcium in an mGluR5 in vitro efficacy assay. In the present study we report
Olson, Jeremy P.,Gichinga, Moses G.,Butala, Elizabeth,Navarro, Hernan A.,Gilmour, Brian P.,Carroll, F. Ivy
experimental part
p. 4276 - 4286
(2011/07/29)
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