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2,3-Pyridinediamine,4-methoxy-(9CI) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 127356-16-5 Structure
  • Basic information

    1. Product Name: 2,3-Pyridinediamine,4-methoxy-(9CI)
    2. Synonyms: 2,3-Pyridinediamine,4-methoxy-(9CI);2,3-Diamino-4-methoxypyridine;4-methoxypyridine-2,3-diamine
    3. CAS NO:127356-16-5
    4. Molecular Formula: C6H9N3O
    5. Molecular Weight: 139.16
    6. EINECS: N/A
    7. Product Categories: PYRIDINE
    8. Mol File: 127356-16-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 335.1±37.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.251±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 7.76±0.47(Predicted)
    10. CAS DataBase Reference: 2,3-Pyridinediamine,4-methoxy-(9CI)(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2,3-Pyridinediamine,4-methoxy-(9CI)(127356-16-5)
    12. EPA Substance Registry System: 2,3-Pyridinediamine,4-methoxy-(9CI)(127356-16-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 127356-16-5(Hazardous Substances Data)

127356-16-5 Usage

Synthesis Reference(s)

Journal of Medicinal Chemistry, 33, p. 2231, 1990 DOI: 10.1021/jm00170a030

Check Digit Verification of cas no

The CAS Registry Mumber 127356-16-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,3,5 and 6 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 127356-16:
(8*1)+(7*2)+(6*7)+(5*3)+(4*5)+(3*6)+(2*1)+(1*6)=125
125 % 10 = 5
So 127356-16-5 is a valid CAS Registry Number.

127356-16-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-methoxypyridine-2,3-diamine

1.2 Other means of identification

Product number -
Other names 2,3-Diamino-4-methoxypyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:127356-16-5 SDS

127356-16-5Relevant articles and documents

Polycyclic compound for inhibiting RNA helicase DHX33

-

Paragraph 0240; 0244-0246, (2021/04/17)

The invention relates to a polycyclic compound for inhibiting RNA helicase DHX33. In particular, the invention relates to a compound shown as a formula I or a pharmaceutically acceptable form thereof, a pharmaceutical composition containing the compound, a preparation method of the compound, and medical application of the compound to prevention and/or treatment of DHX33 related diseases.

SUBSTITUTED BENZIMIDAZOLE CARBOXAMIDES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

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Paragraph 00442-00443, (2021/04/01)

The invention provides substituted benzimidazole carboxamides and related compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat a medical disorder, e.g., cancer, lysosomal storage disorder, neurodegenerative disorder, inflammatory disorder, in a patient.

A model D - amino acid oxidase inhibitor and its preparation and application

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Paragraph 0319; 0321, (2019/02/02)

The invention provides a novel D- amino acid oxidase inhibitor and a preparation and application thereof. In particular, the invention discloses derivatives of quinoxaline-2,3-diketone, which has a novel structure shown in formula A, as well as a preparation method thereof and an application as an inhibitor of D-amino acid oxidase (DAAO). The compound provided by the invention shows excellent effects of analgesia and blocking morphine analgesia tolerance, and has application value for analgesia, treating opiate drug tolerance, and anti-schizophrenia.

2-(HETERO)ARYL-BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AS INHIBITORS OF ASPARAGIME EMETHYL TRANSFERASE

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Page/Page column 59; 60, (2014/09/03)

Substituted benzimidazole and 3H-imidazo[4,5-b]pyridines or formula I: where X and Y respectively are selected from: (i) N and N; and (ii) N and CR4; A2 is selected from:, a C5 heteroarylene group, containing 2 or 3 ring heteroatoms, where the bonds to L1 and the core are β to one another; L1 is selected from: (i)A1-O-CH2-A2; (ii)A1-CH2-O-A2; (iii)A1-C(=O)-NH-A2; (iv)A1-CH(OH)-A2; (v)A1-CH2-NH-C(=O)-A2; (vi) A1-S-CH2-A2; (vii)A1- CH2-S-A2; (viii)A1-CH2-A2; and (ix)A1-CH(CH3)-O-A2; A1 is phenyl, optionally substituted by F or CF3; their use as pharmaceuticals, and in particular, in treating cancer and hemoglobinopathies.

PYRIDINE COMPOUNDS AND USES THEREOF

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Page/Page column 19, (2013/03/26)

The present invention is directed to pyridine compounds of Formula (I). Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds as therapeutic agents treating neurological and psych

Diaminopyridine compounds and methods of use

-

, (2008/06/13)

The present invention relates to compositions and method for inhibiting nonenzymatic cross-linking (protein aging) which contain diaminopyridines and derivates thereof. Accordingly, a composition is disclosed which comprises an agent capable of inhibiting the formation of advanced glycosylation endproducts of target proteins by reacting with the carbonyl moiety of the early glycosylation product of such target proteins formed by their initial glycosylation. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.

Inotropic 'A' ring substituted sulmazole and isomazole analogues

Barraclough,Black,Cambridge,Collard,Firmin,Gerskowitch,Glen,Giles,Hill,Hull,Iyer,King,Kneen,Lindon,Nobbs,Randall,Shah,Smith,Vine,et al.

, p. 2231 - 2239 (2007/10/02)

A series of 'A' ring substituted sulmazole and isomazole analogues have been prepared and evaluated as inotropic agents. pK(A)'s, protonation sites, and log P values were measured for selected compounds and their electronic properties were calculated. No simple correlation between inotropic activity and pK(A), protonation site, or log P value was observed. However, in vitro inotropism did correlate with the calculated charge density of the 'B' ring imidazo nitrogen atom. The 6-position of sulmazole appeared to be the most tolerant toward substituents, th 6-amino derivative 7 being a more potent inotrope than sulmazole itself. 4-Methoxyisomazole 13 had comparable in vivo inotropic properties to those of isomazole.

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