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Magnolin, a natural polyphenol compound, is derived from the bark and flower buds of the magnolia tree. It exhibits a range of health-promoting properties, including anti-inflammatory, antioxidant, and anticancer activities. MAGNOLIN's potential health benefits have been the subject of ongoing research, with studies focusing on its ability to inhibit cancer cell growth and reduce inflammation. Magnolin's significant antioxidant activity also contributes to its protective effects on cells against free radical damage.

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  • 1275595-33-9 Structure
  • Basic information

    1. Product Name: MAGNOLIN
    2. Synonyms: rel-(7S7'S8R8'R)-Magnolin;1H,3H-Furo[3,4-c]furan, 1-(3,4-dimethoxyphenyl)tetrahydro-4-(3,4,5-trimethoxyphenyl)-, (1R,3aS,4R,6aS)-rel-
    3. CAS NO:1275595-33-9
    4. Molecular Formula: C23H28O7
    5. Molecular Weight: 416.46
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1275595-33-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: MAGNOLIN(CAS DataBase Reference)
    10. NIST Chemistry Reference: MAGNOLIN(1275595-33-9)
    11. EPA Substance Registry System: MAGNOLIN(1275595-33-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1275595-33-9(Hazardous Substances Data)

1275595-33-9 Usage

Uses

Used in Pharmaceutical Industry:
Magnolin is used as an anticancer agent for its potential to inhibit the growth of cancer cells. It has been studied for its effects on various types of cancer, including its ability to modulate oncological signaling pathways and exert inhibitory effects on tumor growth and progression.
Used in Nutraceutical Industry:
Magnolin is used as a dietary supplement for its antioxidant properties, which help protect cells from damage caused by free radicals. Its anti-inflammatory and health-promoting benefits make it a valuable addition to nutraceutical products aimed at enhancing overall well-being.
Used in Dermatological Applications:
In the cosmetic and skincare industry, Magnolin is used as an ingredient in various products for its potential to treat skin disorders and promote skin health. Its anti-inflammatory and antioxidant properties contribute to its effectiveness in addressing skin-related issues.
Used in Neurodegenerative Disease Treatment:
Magnolin is being investigated for its potential use in treating neurodegenerative diseases due to its neuroprotective properties. Its ability to reduce inflammation and oxidative stress in the brain may contribute to its therapeutic effects in this area.
Used in Cardiovascular Disease Management:
Research is being conducted on Magnolin's potential role in managing cardiovascular diseases. Its anti-inflammatory and antioxidant properties may help in reducing inflammation and oxidative stress associated with these conditions, thus promoting heart health.

Check Digit Verification of cas no

The CAS Registry Mumber 1275595-33-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,7,5,5,9 and 5 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1275595-33:
(9*1)+(8*2)+(7*7)+(6*5)+(5*5)+(4*9)+(3*5)+(2*3)+(1*3)=189
189 % 10 = 9
So 1275595-33-9 is a valid CAS Registry Number.

1275595-33-9Downstream Products

1275595-33-9Relevant articles and documents

A LIGNAN FROM LINDERA PRAECOX

Ichino, Kazuhiko,Tanaka, Hitoshi,Ito, Kazuo

, p. 1906 - 1907 (1988)

A new 2,6-diaryl-3,7-dioxabicyclooctane lignan, praderin, was isolated from the leaves of Lindera praecox.Key Word Index-Lindera praecox; Lauraceae; lignan; praderin; isomagnolin; philligenin.

Total synthesis of (±)-epimagnolin A

Brown, Richard C.D.,Bataille, Carole J.R.,Hinks, Jeremy D.

, p. 473 - 475 (2001)

The first total synthesis of (±)-epigmagnolin A was was achieved employing a C-H insertion reaction reaction to generate selectively the bicyclic framework with the exo, endo-stereochemistry.

C-H insertion approach to the synthesis of endo,exo-furofuranones: Synthesis of (±)-asarinin, (±)-epimagnolin A, and (±)-fargesin

Brown,Bataille,Bruton,Hinks,Swain

, p. 6719 - 6728 (2007/10/03)

A series of novel 5-aryl-4-aryloxymethyl-3-diazotetrahydrofuran-2-ones (12, 24, and 35a/b) have been prepared and found to undergo regio- and stereoselective C-H insertion reactions to afford 2,6-diaryl-3,7-dioxabicyclo[3.3.0]octane-8-ones (18, 26, and 36a/b) with endo,exo stereochemistry. Subsequent reduction of the lactone ring and cyclization of the resulting diols 27 and 37a/b permitted the synthesis of three endo, exo-furofuran lignans: asarinin (2), fargesin (3), and epimagnolin A (4). En route to the key diazo compounds 24 and 35a/b, a modified procedure for the Ghosez keteniminium-olefin cyclization was developed, which was required to minimize the decomposition of acid-sensitive functional groups such as electron-rich benzylic ethers that were present in the target compounds 2-4.

(-)-Magnofargesin and (+)-magnoliadiol, two lignans from Magnolia fargesii

Miyazawa, Mitsuo,Kasahara, Hiroyuki,Kameoka, Hiromu

, p. 531 - 533 (2007/10/03)

Two new lignans, (-)-magnofargesin and (+)-magnoliadiol, were isolated from the flower buds of Magnolia fargesii. The absolute configuration assignment of (-)-magnofargesin was achieved by its isomerization to (+)-magnolin.

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