An improved synthesis of natural product inspired chromenopyrrolizines and chromenoindolizines scaffolds: Rapid access to the diverse pyrrolizine analogs of aza-medicarpin and tetracyclic isolamellarin core through a general base and metal free strategy
An improved synthesis for easy access to the natural product inspired chromenopyrrolizine and chromenoindolizine scaffolds is delineated. The strategy involves controlled thermal activation of diverse salicylaldehyde tethered dipolarophiles having the str
Khan, Tabrez,Kumar, Virendra,Das, Oindreela
p. 1331 - 1340
(2017/08/02)
N-heterocyclic carbene catalyzed intramolecular hydroacylation of activated alkynes: Synthesis of chromones
An organocatalytic intramolecular Stetter-type hydroacylation reaction between an aldehyde and an activated alkyne has been developed. This study induces salicylaldehyde-derived alkyne derivatives to assemble into a series of chromone derivatives using a