Compounds, methods of use, and processes for making inhibitors of complement Factor D comprising Formula (I), or a pharmaceutically acceptable salt or composition thereof The inhibitors described herein target Factor D and inhibit or regulate the complement cascade. The inhibitors of Factor D described herein reduce the excessive activation of complement.
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Paragraph 0560
(2017/03/14)
CERTAIN PROTEIN KINASE INHIBITORS
Provided are certain EGFR mutant selective inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
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(2016/01/01)
Polarized Ethylene. V. Synthesis of 1-Substituted Indolizine, Pyrazolopyridine, and Their Related Compounds Using Methoxyethylene Derivatives
The reaction of pyridinium or isoquinolinium N-ylides with methoxy-substituted ethylenes gave the corresponding indolizine and pyrroloisoquinoline derivatives bearing acetyl, aroyl, cyano, ester group at the 1-position in one step.Pyrazolopy