1126444-46-9Relevant articles and documents
Iodine-Catalyzed Radical Oxidative Annulation for the Construction of Dihydrofurans and Indolizines
Tang, Shan,Liu, Kun,Long, Yue,Gao, Xinlong,Gao, Meng,Lei, Aiwen
, p. 2404 - 2407 (2015)
Through iodine catalysis, the direct oxidative coupling/annulation of β-keto esters or 2-pyridinyl-β-esters with alkenes was achieved. This reaction procedure provides a simple and selective way for the synthesis of dihydrofurans and indolizines in one st
Palladium-catalyzed C-3 desulfitative arylation of indolizines with sodium arylsulfinates and arylsulfonyl hydrazides
Wang, Chunjie,Jia, Huali,Li, Zhiwei,Zhang, Hui,Zhao, Baoli
, p. 21814 - 21821 (2016/03/08)
Derivatized indolizines were efficiently prepared by direct C-3 arylation of indolizines using sodium arylsulfinates and arylsulfonyl hydrazides. Pd-catalyzed desulfitative C-3 arylation with sodium arylsulfinates was achieved with the assistance of peroxides, and the catalytic efficiency was promoted by N-containing ligands. Arylsulfonyl hydrazides were also successfully applied in Pd-catalyzed desulfitative C-3 arylation with indolizines, and the side homocoupling reactions can be restrained in the component solvent under milder conditions. Various derivatives were synthesized in good yields by both methods, offering expedient protocols for the synthesis of C-3 functionalized indolizine molecules.
Tuning radical reactivity using iodine in oxidative C(sp3)-H/C(sp)-H cross-coupling: An easy way toward the synthesis of furans and indolizines
Tang, Shan,Liu, Kun,Long, Yue,Qi, Xiaotian,Lan, Yu,Lei, Aiwen
supporting information, p. 8769 - 8772 (2015/05/20)
Molecular iodine was found to be an effective redox catalyst for the oxidative cross-coupling of carbonyl compounds with terminal alkynes. In this work, we demonstrated that iodine could tune radical reactivity through reversible C-I bond formation for co
