Synthesis of aryl urea derivatives from aryl amines and aryl isocyanates
The present study describes the synthesis of novel diaryl urea derivatives derived from aryl amine and aryl isocyanates. The synthesized compounds are analogs of sorafenib [4-[4-[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl] amino]phenoxy]-N-methylpyridine-2- carboxamide] having potential antiproliferative activity.
Usharani,Bhujanga Rao,Reddy,Dubey
p. 1802 - 1806
(2011/12/22)
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