cas 129-20-4, OXYPHENYL BUTAZONE | Articles data ｜lookchem

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129-20-4

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Contraceptive method
Contraceptive method comprises maintaining in the genital tract of a female mammal a pyrazolone derivative in a concentration effective to inhibit the fertilization of ova. In addition to effectively inhibiting the enzymes or other sperm components necessary for conception, the compounds used in the method of the invention are advantageous in having low toxic, caustic or irritating properties, so that the contraceptive compositions are suitable for long-term use without adverse side-effects.
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(2008/06/13)

Quality control of phenylbutazone I: Analysis of phenylbutazone and decomposition products in drugs by TLC
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Fabre,Mandrou
p. 460 - 461
(2007/10/02)

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Chemical Properties

Melting Point: 109-111°C
Boiling Point: 485.6°Cat760mmHg
Flash Point:247.5°C
Density: 1.241g/cm³
Solubility:DMSO: soluble10mg/mL, clear
Storage Temp.:Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Vapor Pressure: 4.7E-10mmHg at 25°C
Refractive Index: 1.6140 (estimate)
PKA: pKa 4.7/10.0±0.2(H2O,t =25,Iundefined) (Uncertain)
PSA: 60.85000
LogP: 3.62340

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