129003-87-8

Basic information

• Product Name: Ethanone, 1-(1-methyl-1H-imidazol-4-yl)- (9CI)
• Synonyms: Ethanone, 1-(1-methyl-1H-imidazol-4-yl)- (9CI);Ethanone, 1-(1-Methyl-1H-iMidazol-4-yl)-;1-(1-Methyl-1H-imidazol-4-yl)ethanone;4-Acetyl-1-methyl-1H-imidazole
• CAS NO: 129003-87-8
• Molecular Formula: C6H8N2O
• Molecular Weight: 124.14052
• Product Categories: ACETYLGROUP;AMINETERTIARY
• Mol File: 129003-87-8.mol

Chemical Properties

• Boiling Point: 289℃
• Flash Point: 128℃
• Appearance: /
• Density: 1.11
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.14±0.61(Predicted)
• CAS DataBase Reference: Ethanone, 1-(1-methyl-1H-imidazol-4-yl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(1-methyl-1H-imidazol-4-yl)- (9CI)(129003-87-8)
• EPA Substance Registry System: Ethanone, 1-(1-methyl-1H-imidazol-4-yl)- (9CI)(129003-87-8)

Safety Data

• Hazardous Substances Data: 129003-87-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Ethanone, 1-(1-methyl-1H-imidazol-4-yl)(9CI) is used as a pharmaceutical intermediate for the development of various drugs. Its unique structure and reactivity allow it to be a key component in the synthesis of new pharmaceutical compounds, potentially leading to the discovery of novel therapeutic agents.
Used in Organic Synthesis:
As a valuable building block, Ethanone, 1-(1-methyl-1H-imidazol-4-yl)(9CI) is used in organic synthesis for the creation of a wide range of organic compounds. Its imidazole ring and methyl group provide opportunities for further chemical reactions and modifications, making it a versatile component in the synthesis of various organic molecules.
Used in Research:
Ethanone, 1-(1-methyl-1H-imidazol-4-yl)(9CI) is also utilized in research settings to study its properties, reactivity, and potential applications. Researchers can use this compound to explore new chemical reactions, investigate its interactions with other molecules, and develop a deeper understanding of its role in organic chemistry and potential uses in various industries.

Upstream product

• 873221-68-2 1-methyl-1H-imidazole-4-carboxylic acid N-methoxy-N-methylamide 
• 917-54-4 methyllithium 
• 1202769-48-9 4-(1-methoxyethenyl)-1-methyl 1-methyl-1H-imidazole 
• 17289-19-9 methyl 1-methyl-1H-imidazole-4-carboxylate 
• 75-16-1 methylmagnesium bromide 
• 66121-69-5 1-methyl-1H-imidazole-4-carbonitrile 

Relevant articles and documents

AMINO-INDOLYL-SUBSTITUTED IMIDAZOLYL-PYRIMIDINES AND THEIR USE AS MEDICAMENTS

The invention relates to new amino-indole-substituted imidazolyl-pyrimidines of formula (1), wherein R1, R2, R3, R4 and R5 are defined as in claim 1 and pharmaceutically acceptable salts thereof and the use of these compounds for the preparation of a medicament for treating a disease selected from asthma, COPD, rheumatoid arthritis, specific lymphomas and specific diseases of the nervous system

Amino-Indolyl-Substituted Imidazolyl-Pyrimidines and Their Use as Medicaments

The invention relates to new amino-indole-substituted imidazolyl-pyrimidines of formula 1 wherein R1, R2, R3, R4 and R5 are defined as in claim 1 and pharmaceutically acceptable salts thereof and the use of these compounds for the preparation of a medicament for treating a disease selected from asthma, COPD, rheumatoid arthritis, specific lymphomas and specific diseases of the nervous system.

ALKYNYL ALCOHOLS AS KINASE INHIBITORS

Selected compounds are effective for prophylaxis and treatment of inflammation and inflammatory disorders, such as NIK-mediated disorders. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, inflammation and the like.

PYRAZOLE DERIVATIVE

A compound represented by Formula (I): wherein Ar1 represents Formula (II): Ar2 represents a 5- or 6-membered aromatic heterocyclic group which may be substituted; and X represents Formula (III): a salt thereof, or a solvate of the compound or the salt. A potent platelet aggregation suppressant which does not inhibit COX-1 and COX-2 is provided.

PYRAZOLE DERIVATIVES

A compound represented by formula (I): (wherein Ar1 represents a phenyl group which may have 1 to 3 substituents, or a non-substituted 5- or 6-membered aromatic heterocyclic group; Ar2 represents (i) a non-substituted phenyl group, (ii) a phenyl group which has been substituted by a lower alkyl group having 1 to 3 groups or atoms selected from among a carbamoyl group, an amino group, a hydroxyl group, a lower alkoxy group, and a halogen atom, or (iii) a 5- or 6-membered nitrogen-containing aromatic heterocyclic group which has been substituted by 1 to 3 groups or atoms selected from among a lower alkyl group, a lower alkynyl group, a lower alkanoyl group, a carbamoyl group, a cyano group, an amino group, a hydroxyl group, a lower alkoxy group, and a halogen atom; and X represents a group represented by formula (II): (wherein the ring structure represents a 4- to 7-membered heterocyclic group which may have, in addition to the nitrogen atom shown in formula (II), one heteroatom selected from among nitrogen, oxygen, and sulfur, and which may be substituted by 1 to 4 groups or atoms selected from among a lower alkyl group, a carbamoyl group, an amino group, a hydroxyl group, a lower alkoxy group, an oxo group, a lower alkanoyl group, a lower alkylsulfonyl group, and a halogen atom)), a salt thereof, a solvate of the compound or the salt, and a drug.