A FACILE SYNTHESIS OF 6-AMINO-1-BENZYL-4-METHYL- AND 6-AMINO-1,4-DIMETHYLHEXAHYDRO-1H-1,4-DIAZEPINES, THE AMINE PART OF SUBSTITUTED BENZAMIDES WITH A POTENT SEROTONIN 3 RECEPTOR ANTAGONISTIC ACTIVITY
A facile synthesis of 6-amino-1-benzyl-4-methyl- and 6-amino-1,4-dimethylhexahydro-1H-1,4-diazepines (16a and 16b) which have served as the amine part of the new and novel benzamides (3 and 4) with a potent serotonin 3 receptor antagonistic activity is re