129993-47-1 Usage
Uses
Used in Pharmaceutical Synthesis:
1-Methyl-1H-imidazole-4-carboxamide is used as a building block in the synthesis of various pharmaceuticals due to its versatile chemical properties and biological activities, which include anti-bacterial, anti-fungal, and anti-tumor effects.
Used in Drug-Development Research:
As a compound with demonstrated biological activities, 1-Methyl-1H-imidazole-4-carboxamide is utilized as a valuable precursor in drug-development research, where it can be further modified or combined with other compounds to create new therapeutic agents.
Used in Organic Chemistry:
1-Methyl-1H-imidazole-4-carboxamide is employed as a versatile building block in organic chemistry, allowing for the creation of a wide range of chemical compounds with potential applications in various fields.
Used in Gene Expression Regulation:
1-Methyl-1H-imidazole-4-carboxamide is used in the study and regulation of gene expression, potentially contributing to the development of treatments for genetic disorders and other conditions influenced by gene regulation.
Used in Therapeutic Applications for Cardiovascular and Neurological Conditions:
Given its potential as a therapeutic agent, 1-Methyl-1H-imidazole-4-carboxamide is being explored for use in the treatment of cardiovascular and neurological conditions, where its biological activities may offer novel avenues for intervention and management.
Check Digit Verification of cas no
The CAS Registry Mumber 129993-47-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,9,9 and 3 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 129993-47:
(8*1)+(7*2)+(6*9)+(5*9)+(4*9)+(3*3)+(2*4)+(1*7)=181
181 % 10 = 1
So 129993-47-1 is a valid CAS Registry Number.
InChI:InChI=1/C5H7N3O/c1-8-2-4(5(6)9)7-3-8/h2-3H,1H3,(H2,6,9)
129993-47-1Relevant articles and documents
HETEROARYL ALKYLENE SUBSTITUTED 2-OXOQUINAZOLINE DERIVATIVES AS INHIBITORS OF METHIONINE ADENOSYLTRANSFERASE 2A
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Paragraph 0366, (2021/12/31)
Disclosed herein are certain heteroaryl alkylene substituted 2-oxoquinazoline derivatives of Formula (I): (I) that are methionine adenosyltransferase 2A (MAT2A) inhibitors. Also disclosed are pharmaceutical compositions comprising such compounds and methods of treating diseases treatable by inhibition of MAT2A such as cancer, including cancers characterized by reduced or absence of methylthioadenosine phosphorylase (MTAP) activity.
SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF
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Paragraph 00411, (2018/08/03)
Provided herein are small molecule activators of Nicotinamide Phosphoribosyltransferase (NAMPT), compositions comprising the compounds, and methods of using the compounds and compositions.
Thiazole benzamide derivatives and pharmaceutical compositions for inhibiting cell proliferation, and methods for their use
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Page 37-38, (2010/02/03)
Aminothiazole compounds with mono-/di-substituted benzamide are represented by the Formula (I), and their pharmaceutically acceptable salts, pharmaceutically acceptable prodrugs, pharmaceutically active metabolites, and pharmaceutically acceptable salts of said metabolites are described. These agents modulate and/or inhibit the cell proliferation and activity of protein kinases and are useful as pharmaceuticals for treating malignancies and other disorders.
SELECTIVE ALKYLATION OF IMIDAZOLE-4(5)-CARBOXAMIDES
Piotrovskii, L. B.,Dumpis, M. A.
, p. 407 - 409 (2007/10/02)
Alkylation of imidazole-4(5)-carboxamides by alkyl halides or dimethylsulfate leads to the selective formation of 1-alkyl-imidazole-4-carboxamides.
