- Synthesis and antimicrobial evaluation of oxazole-2(3H)-thione and 2-alkylsulfanyl-1,3-oxazole derivatives
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The preparation of oxazole-2(3H)-thiones (OXTs) by condensation of thiocyanic acid on α-hydroxycarbonyl substrates has been revisited. Extension to more complex scaffolds afforded chiral OXTs, whereas carbohydrate-fused 2-alkylsulfanyl-1,3-oxazolines led
- Silva, Sandrina,Silva, Filipa V. M.,Justino, Jorge,Rauter, Amelia Pilar,Rollin, Patrick,Tatibouet, Arnaud
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p. 1013 - 1028
(2014/01/17)
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- Aromatic or chiral heterocycle - Balance between 1,3-oxazoline-2-thione and 1,3-oxazolidine-2-thione
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1,3-Oxazoline-2-thiones (OXT) and bis-1,3-oxazol-idine-2-thiones (bis-OZT) were selectively prepared depending on the conditions and starting materials used, and then underwent some N- and S-selective reactions. Georg Thieme Verlag Stuttgart.
- Leconte, Nicolas,Silva, Sandrina,Tatibou?t, Arnaud,Rauter, Amelia P.,Rollin, Patrick
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p. 301 - 305
(2007/10/03)
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- Nematicidal trifluorobutenes
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The present invention relates to novel trifluorobutenes of the formula (I) 1wherein R1 represents hydrogen, halogen, or alkyl which may be unsubstituted or substituted with halogen, hydroxy, alkoxy, alkylthio, alkylcarbonyloxy, haloalkylcarbonyloxy or cyano, or represents alkylsulfonyloxy or represents phenyl which may be unsubstituted or substituted with halogen, alkyl, haloalkyl, alkoxy, alkylthio, alkylsulfonyl, haloalkoxy, haloalkylthio, phenyl, phenoxy, cyano or nitro. R2 represents hydrogen, halogen, or alkyl which may be unsubstituted or substituted with alkoxy or halogen, or represents alkoxycarbonyl, and n represents 0, 1 or 2, provided that if R1 represents alkyl, R2 does not represent halogen, processes for their preparation and their use as nematicides.
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- Cephalosporin compounds and antibacterial agents
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Cephalosporin compounds of the formula (I): STR1 wherein R1 and R2 may be the same or different and are a hydrogen atom or a lower alkyl group of 1-5 carbon atoms and A is a hydrogen atom or a nucleophilic compound residue or pharmacologically acceptable salts thereof have excellent antibacterial activity against Gram positive and Gram negative microorganisms.
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