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Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
4-methyl-1,3-oxazole-2(3H)-thione is used as a precursor for the synthesis of pharmaceuticals and agrochemicals due to its versatile chemical properties and potential for creating a wide range of compounds.
Used as an Antimicrobial Preservative:
4-methyl-1,3-oxazole-2(3H)-thione is used as an antimicrobial preservative in various consumer products such as cosmetics, personal care products, and household cleaners, thanks to its antimicrobial properties.
Used in the Development of New Antimicrobial Agents:
4-methyl-1,3-oxazole-2(3H)-thione is being studied for its potential use in the development of new antimicrobial agents, indicating its importance in the ongoing search for effective treatments against resistant microbes.
While 4-methyl-1,3-oxazole-2(3H)-thione is generally regarded as safe for use in consumer products, further studies on its potential environmental and human health impacts are still ongoing to ensure its safe and responsible use.

Upstream product

• 333-20-0 potassium thioacyanate 
• 116-09-6 hydroxy-2-propanone 

Downstream Products

• 116672-02-7 5-(4-Methyl-oxazol-2-ylsulfanyl)-2-phenyl-4-trifluoromethyl-oxazole 
• 62124-50-9 2-benzylsulfanyl-4-methyl-1,3-oxazole 
• 886040-38-6 2-(benzoylmethyl)sulfanyl-4-methyl-1,3-oxazole 
• 886040-45-5 2-[(2-phenylsulfonyl)ethyl]sulfanyl-4-methyl-1,3-oxazole 
• 666752-85-8 2-[[(2,3-difluorophenyl)methyl]thio]-6-[[(1R)-2-hydroxy-1-methylethyl]amino]-5-[(4-methyl-2-oxazolyl)thio]-4-pyrimidinol 

Relevant academic research and scientific papers

Synthesis and antimicrobial evaluation of oxazole-2(3H)-thione and 2-alkylsulfanyl-1,3-oxazole derivatives

The preparation of oxazole-2(3H)-thiones (OXTs) by condensation of thiocyanic acid on α-hydroxycarbonyl substrates has been revisited. Extension to more complex scaffolds afforded chiral OXTs, whereas carbohydrate-fused 2-alkylsulfanyl-1,3-oxazolines led

Aromatic or chiral heterocycle - Balance between 1,3-oxazoline-2-thione and 1,3-oxazolidine-2-thione

1,3-Oxazoline-2-thiones (OXT) and bis-1,3-oxazol-idine-2-thiones (bis-OZT) were selectively prepared depending on the conditions and starting materials used, and then underwent some N- and S-selective reactions. Georg Thieme Verlag Stuttgart.

Nematicidal trifluorobutenes

The present invention relates to novel trifluorobutenes of the formula (I) 1wherein R1 represents hydrogen, halogen, or alkyl which may be unsubstituted or substituted with halogen, hydroxy, alkoxy, alkylthio, alkylcarbonyloxy, haloalkylcarbonyloxy or cyano, or represents alkylsulfonyloxy or represents phenyl which may be unsubstituted or substituted with halogen, alkyl, haloalkyl, alkoxy, alkylthio, alkylsulfonyl, haloalkoxy, haloalkylthio, phenyl, phenoxy, cyano or nitro. R2 represents hydrogen, halogen, or alkyl which may be unsubstituted or substituted with alkoxy or halogen, or represents alkoxycarbonyl, and n represents 0, 1 or 2, provided that if R1 represents alkyl, R2 does not represent halogen, processes for their preparation and their use as nematicides.

Cephalosporin compounds and antibacterial agents

Cephalosporin compounds of the formula (I): STR1 wherein R1 and R2 may be the same or different and are a hydrogen atom or a lower alkyl group of 1-5 carbon atoms and A is a hydrogen atom or a nucleophilic compound residue or pharmacologically acceptable salts thereof have excellent antibacterial activity against Gram positive and Gram negative microorganisms.