130186-64-0Relevant articles and documents
Synthesis of 4-methyl-2,3-disubstituted quinoline scaffolds via environmentally benign Fe(iii) catalysed sequential condensation, cyclization and aromatization of 1,3-diketone and 2-ethynylaniline
Sivaraman, Mahalingam,Perumal, Paramasivan T.
, p. 52060 - 52066 (2014/12/10)
Environmentally benign Fe(iii)-catalysed sequential condensation, cyclization and aromatization of 1,3-diketone and 2-ethynylaniline derivatives to the substituted quinoline scaffolds with good to excellent yield in shorter reaction time is described. This journal is
Sulfuric acid-modified PEG-6000 (PEG-OSO3H): An efficient, bio-degradable and reusable polymeric catalyst for the solvent-free synthesis of poly-substituted quinolines under microwave irradiation
Hasaninejad, Alireza,Zare, Abdolkarim,Shekouhy, Mohsen,Ameri-Rad, Javad
experimental part, p. 958 - 964 (2011/05/12)
Sulfuric acid-modified polyethylene glycol 6000 (PEG-OSO3H) is applied as an efficient and eco-friendly polymeric catalyst for Friedlaender synthesis of poly-substituted quinolines from 2-aminoaryl ketones (or anthranilonitrile) and carbonyl compounds possessing a reactive methylene group under microwave irradiation and solvent-free conditions. The reactions are completed in short times, and the products are obtained in good to excellent yields. The Royal Society of Chemistry.
Synthesis and crystal structure of 7,8-dihydroquinolino[2,3-a]acridine derivatives
Han, Guang-Fan,Wang, Rui-Hua,Zhang, Wen-Tao,Zhao, Yu-Yuan,Xing, Zheng,Dai, Wei
experimental part, p. 2492 - 2505 (2009/12/06)
Novel 9-amino-3-substituted-1,2,3,4-acridin-1-one derivatives and 9,14-diamino-7-substituted-7,8-dihydroquinolino[2,3-a]acridine derivatives were synthesized by the condensation reaction of 5-substituted-1,3-cyclohexanedione with 2-aminobenzonitrile and s
9-aminoacridine derivatives possessing psychotropic, antiamnestic and lipid-regulative activity
-
, (2008/06/13)
"Derivatives of 9-aminoacridine characterized by psychothropic, antiamnestic and lipid-regulating activities". New chemical compounds derived of 9-aminoacridine with a general formula are presented: STR1 where R=H or CH3 R1 =H, CHsu
DERIVATIVES OF 9-AMINOACRIDINE HAVING PSYCHOTROPIC, ANTIAMNESTIC AND LIPID REGULATING PROPERTIES
-
, (2008/06/13)
New chemical compounds, derivatives of 9-aminoacridine of general formula (I) where R = H, CH3; R1 = H, CH3, Br; R2 = H, CH3; R3 = alkyl-C1-C5, arylmethyl, diethylaminoethyl; X = C = O, CHOH; Y = CH2; X + Y = CH = CH; and their salts with organic and non-organic acids. The desired compounds are obtained by interaction of substituted nitriles of antranyl acid with dimedone with subsequent cyclization of intermediate enaminonitriles into corresponding ketones of 9-aminoacridine after the reduction of which and of their derivatives alkylated or aralkylated on the 9-amino group, the corresponding alcohols are obtained, after hydration of which 9-amino-3,4-dihydroacridines are obtained. When experimented on animals, the said derivatives of 9-aminoacridine have shown psychotropic, antiamnestic and lipid regulating properties, as well as a lower toxicity in comparison with known preparations.
Acridine derivatives
-
, (2008/06/13)
A compound of the formula : wherein R1 is hydrogen, halogen, hydroxy, lower alkoxy, lower alkyl or mono(or di or tri)halo(lower)alkyl, and (in which R2 and R3 are each lower alkyl),and a pharmaceutically acceptable salt thereof, processes for their prepar