130734-37-1

Basic information

• Product Name: METHYL 2-METHYL-4-(4-NITROPHENYL)-6-OXO-1,4,5,6-TETRAHYDRO-3-PYRIDINECARBOXYLATE
• Synonyms: METHYL 2-METHYL-4-(4-NITROPHENYL)-6-OXO-1,4,5,6-TETRAHYDRO-3-PYRIDINECARBOXYLATE;methyl 2-methyl-4-(4-nitrophenyl)-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate
• CAS NO: 130734-37-1
• Molecular Formula: C₁₄H₁₄N₂O₅
• Molecular Weight: 290.27
• Mol File: 130734-37-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: METHYL 2-METHYL-4-(4-NITROPHENYL)-6-OXO-1,4,5,6-TETRAHYDRO-3-PYRIDINECARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-METHYL-4-(4-NITROPHENYL)-6-OXO-1,4,5,6-TETRAHYDRO-3-PYRIDINECARBOXYLATE(130734-37-1)
• EPA Substance Registry System: METHYL 2-METHYL-4-(4-NITROPHENYL)-6-OXO-1,4,5,6-TETRAHYDRO-3-PYRIDINECARBOXYLATE(130734-37-1)

Safety Data

• Hazardous Substances Data: 130734-37-1(Hazardous Substances Data)

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 555-16-8 4-nitrobenzaldehdye 
• 105-45-3 acetoacetic acid methyl ester 
• 67-56-1 methanol 
• 15795-62-7 2,2-dimethyl-5-(4-nitrobenzylidene)-1,3-dioxane-4,6-dione 

Downstream Products

• 1345668-52-1 methyl 6-chloro-5-formyl-2-methyl-4-(4'-nitrophenyl)-1,4-dihydropyridine-3-carboxylate 
• 1356120-80-3 4-(4'-nitrophenyl)-3,4-dihydrofuro[3,4-b]pyridine-2,5-(1H,7H)-dione 

Relevant articles and documents

Rapid microwave-assisted liquid-phase synthesis of 4-substituted-5- methoxycarbonyl-6-methyl-3,4-dihydropyridones on poly(ethylene glycol) support

4-Substituted-5-methoxycarbonyl-6-methyl-3,4-dihydropyridones have been efficiently prepared on the soluble polymer polyethylene glycol (PEG) 4000 by solvent-free microwave irradiation through a one-pot condensation of PEG-bound acetoacetate, Meldrum's acid, ammonium acetate, and the appropriate aldehyde in the presence of a catalytic amount of polyphosphoric acid. The polymer-supported synthesis provided the target compounds in excellent yield and purity with a facile workup procedure. Copyright Taylor & Francis Group, LLC.

Synthesis of 5-carboxy-6-methyl-3,4-dihydro-2(1H)-pyridone derivatives and their electrochemical oxidation to 2-pyridones

A series of variously substituted 5-carboxy-6-methyl-3,4-dihydro-2(1H)-pyridone derivatives were synthesized and their oxidation potentials determined by cyclic voltammetry. The resulting 2-pyridone structure and a tricyclic heterocycle which was formed d

Mesostructured SBA-15-Pr-SO3H: An efficient solid acid catalyst for one-pot and solvent-free synthesis of 3,4-dihydro-2-pyridone derivatives

3,4-Dihydro-2-pyridone derivatives have been prepared efficiently via a one-pot four-component reaction of benzaldehyde derivatives, Meldrum's acid, methyl acetoacetate and ammonium acetate in the presence of sulphonic acid-functionalized ordered nanoporo

Solvent-free synthesis of 4-aryl substituted 5-alkoxycarbonyl-6-methyl-3,4-dihydropyridones under microwave irradiation

4-Aryl substituted 5-alkoxycarbonyl-6-methyl-3,4-dihydropyridones have been prepared in one-pot condensation from Meldrum's acid, methyl acetoacetate and the appropriate benzaldehyde in the presence of ammonium acetate using microwave irradiation without

Solid-phase synthesis of 4-aryl substituted 5-carboxy-6-methyl-3,4-dihydropyridones

Substituted 3,4-dihydro-2-pyridones have been efficiently prepared by solid-phase synthesis using Wang resin from the immobilised β-ketoester and further Hantzsch-type heterocyclisation.

Oxygen-bridged Tetrahydropyridines, Hexahydropyridines, and Dihydropyridones via a Hantzsch-like Synthesis with 4-(2-Hydroxyphenyl)but-3-en-2-one

Substituted oxygen-bridged tetrahydro-2-pyridones and tetrahydropyridines (4) and (7) were synthesized by condensation of 4-(2-hydroxyphenyl)but-3-en-2-one (1) with Meldrum's acid (2) and 3-aminocrotononitrile, respectively, in the presence of ammonium ac