Synthesis of Symmetrical Diaryl Ketones by Cobalt-Catalyzed Reaction of Arylzinc Reagents with Ethyl Chloroformate
Symmetrical diaryl ketones were prepared by a cross-coupling reaction between aryl bromides and ethyl chloroformate. This new method, which uses a catalyst composed of CoBr2and a bipyridine ligand along with readily available starting materials, allows for the synthesis of a variety of symmetrical diaryl ketones in moderate to excellent yields (37–99 %) under mild conditions. This reaction, in which ethyl chloroformate acts as a surrogate of carbon monoxide in the presence of cobalt and zinc, represents an interesting alternative to previously known approaches for the synthesis of diarylmethanones.
IONIC LIQUID SUPPORTED ORGANOTIN REAGENTS FOR THE MANUFACTURING OF RADIOPHARMACEUTICALS COMPOUNDS
The present invention relates to an ionic liquid supported organotin reagent of formula (I). The invention further relates to a process for manufacturing the ionic liquid supported organotin reagent of formula (I) and to a process for manufacturing an hal
-
Page/Page column 81; 82
(2015/07/23)
Microwave-assisted Negishi and Kumada cross-coupling reactions of aryl chlorides
Rapid Pd or Ni-catalyzed microwave-accelerated Negishi and Kumada cross-coupling reactions of aryl chlorides in solution and on solid phase are reported.
Walla, Peter,Kappe, C. Oliver
p. 564 - 565
(2007/10/03)
Ethyl 3-(p-cyanophenyl)propionate from ethyl 3-iodopropionate and p-cyanophenylzinc bromide [ benzenepropanoic acid, 4-cyano-, ethyl ester ]
-
Jensen, Anne Eeg,Kneisel, Florian,Knochel, Paul,Girijavallabhan,Miller, Marvin J.
p. 35 - 35
(2017/09/29)
More Articles about upstream products of 131379-38-9