Regioselective formation of fluorohydrins and their stereoselective conversion to fluoroolefins
When treated with potassium tert-butoxide in tetrahydrofuran, p-toluene-sulfonates derived from fluorohydrins afford fluoroolefins (e.g., Z- or E-3) with high yields. Fluorohydrins are readily and stereoselectively accessible by anti-periplanar addition o