- Enantioselective total synthesis of eudistomidins G, H, and I
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Asymmetric first total synthesis of eudistomidins G, H, and I, tetrahydro-β-carboline alkaloids from the Okinawan marine tunicate Eudistoma glaucus, has been accomplished with the Bischler-Napieralski reaction and the Noyori catalytic asymmetric hydrogen-transfer reaction. The absolute configurations of eudistomidins G, H, and I were confirmed from comparison of the 1H and 13C NMR, and CD spectral data of synthetic and natural eudistomidins G, H, and I, respectively.
- Ishiyama, Haruaki,Yoshizawa, Kazuaki,Kobayashi, Jun'ichi
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p. 6186 - 6192
(2012/08/27)
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