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132018-32-7

Aminogenistein is a yellow solid that inhibits the protein-tyrosine kinase activity of p56lck with an IC50 of 1.2 μM. It is a chemical compound with potential applications in various industries.

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  • 132018-32-7 Structure

  • Basic information

    1. Product Name: Aminogenistein
    2. Synonyms: 4H-1-Benzopyran-4-one,2-(4-aminophenyl)-6-hydroxy-(9CI);2-(4-Aminophenyl)-6-hydroxy-4H-1-benzopyran-4-one;6-Hydroxy-2-(4-aminophenyl)-4H-1-benzopyran-4-one;Aminogenistein, 2-(4-Aminophenyl)-6-hydroxy-4H-chromen-4-one
    3. CAS NO:132018-32-7
    4. Molecular Formula: C15H11NO3
    5. Molecular Weight: 253.2527
    6. EINECS: N/A
    7. Product Categories: FLAVONE;Inhibitors;Protein Kinase Inhibitors and Activators;Tyrosine Kinase Inhibitors
    8. Mol File: 132018-32-7.mol

  • Chemical Properties

    1. Melting Point: 193-194°C
    2. Boiling Point: 516 °C at 760 mmHg
    3. Flash Point: 265.9 °C
    4. Appearance: Yellow Solid
    5. Density: 1.407 g/cm3
    6. Vapor Pressure: 2.87E-11mmHg at 25°C
    7. Refractive Index: 1.709
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. Stability: Light Sensitive
    11. CAS DataBase Reference: Aminogenistein(CAS DataBase Reference)
    12. NIST Chemistry Reference: Aminogenistein(132018-32-7)
    13. EPA Substance Registry System: Aminogenistein(132018-32-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 132018-32-7(Hazardous Substances Data)

132018-32-7 Usage

Uses

Used in Pharmaceutical Industry:
Aminogenistein is used as a pharmaceutical agent for its ability to inhibit protein-tyrosine kinase activity, which can have therapeutic effects on certain diseases and conditions.
Used in Research Applications:
Aminogenistein is used as a research tool for studying the function and regulation of protein-tyrosine kinases, contributing to the understanding of their role in cellular processes and disease mechanisms.
Used in Drug Development:
Aminogenistein is used in drug development as a potential lead compound for the creation of new medications targeting protein-tyrosine kinases, which may have applications in treating various diseases, including cancer and inflammatory conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 132018-32-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,0,1 and 8 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 132018-32:
(8*1)+(7*3)+(6*2)+(5*0)+(4*1)+(3*8)+(2*3)+(1*2)=77
77 % 10 = 7
So 132018-32-7 is a valid CAS Registry Number.
InChI:InChI=1/C15H11NO3/c16-10-3-1-9(2-4-10)15-8-13(18)12-7-11(17)5-6-14(12)19-15/h1-8,17H,16H2

132018-32-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(4-aminophenyl)-6-hydroxychromen-4-one

1.2 Other means of identification

Product number -
Other names Aminogenistein

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:132018-32-7 SDS

132018-32-7Downstream Products

132018-32-7Relevant articles and documents

Synthesis and Protein-Tyrosine Kinase Inhibitory Activities of Flavanoid Analogues

Cushman, Mark,Nagarathnam, Dhanapalan,Burg, Debra L.,Geahlen, Robert L.

, p. 798 - 806 (2007/10/02)

Treatment of o-hydroxyacetophenones 2a-e with excess lithium bis(trimethylsilyl)amide followed by dialkyl carbonates gave 3-(2-hydroxyaryl)-3-oxopropanoates 3a-e.The latter substances were transformed through the reaction of their magnesium chelates with

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