132839-58-8

Basic information

• Product Name: 2-Bromo-1-nitro-4-(trifluoromethyl)benzene
• Synonyms: 2-Bromo-1-nitro-4-(trifluoromethyl)benzene
• CAS NO: 132839-58-8
• Molecular Formula: C₇H₃BrF₃NO₂
• Molecular Weight: 270.01
• Mol File: 132839-58-8.mol

Chemical Properties

• Boiling Point: 224.8±40.0℃ (760 Torr)
• Flash Point: 89.7±27.3℃
• Appearance: Pale yellow/Liquid
• Density: 1.788±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.134mmHg at 25°C
• Refractive Index: 1.514
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-Bromo-1-nitro-4-(trifluoromethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-1-nitro-4-(trifluoromethyl)benzene(132839-58-8)
• EPA Substance Registry System: 2-Bromo-1-nitro-4-(trifluoromethyl)benzene(132839-58-8)

Safety Data

• Hazard Codes: T
• HazardClass: IRRITANT
• Hazardous Substances Data: 132839-58-8(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-Bromo-1-nitro-4-(trifluoromethyl)benzene is utilized as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for a range of chemical reactions, making it a valuable component in the creation of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Bromo-1-nitro-4-(trifluoromethyl)benzene is used as a building block for the development of new drugs. Its presence in the molecular structure can influence the pharmacological properties of the final product, such as potency, selectivity, and bioavailability.
Used in Agrochemical Industry:
2-Bromo-1-nitro-4-(trifluoromethyl)benzene is employed as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides. Its incorporation into these compounds can enhance their effectiveness in controlling pests and weeds, while also potentially reducing the environmental impact.
Safety Precautions:
Due to the potential toxicity and hazardous effects associated with benzene-based compounds, careful handling and disposal procedures are essential when working with 2-Bromo-1-nitro-4-(trifluoromethyl)benzene. This includes the use of appropriate personal protective equipment, containment measures, and adherence to relevant safety regulations.

InChI:InChI=1/C7H3BrF3NO2/c8-5-3-4(7(9,10)11)1-2-6(5)12(13)14/h1-3H

Upstream product

• 402-14-2 2-nitro-5-(trifluoromethyl)aniline 
• 57946-63-1 4-amino-3-bromobenzotrifluoride 

Downstream Products

• 640280-31-5 methyl 5-{[(tert-butoxycarbonyl)amino]methyl}-2-{[2-nitro-5-(trifluoromethyl)phenyl]amino}benzoate 
• 1218791-26-4 2-nitro-5-triflouromethylboronic acid pinacolate ester 
• 491601-38-8 2-phenyl-5-(trifluoromethyl)-1H-indole 
• 2467-83-6 3-(trifluoromethyl)-9H-carbazole 

Relevant articles and documents

Bifunctional iron-amino complexes: Highly efficient catalysts for dehydrogenation of ammonia-borane

Three iron complexes having bidentate 1-(2-aminophenyl)-substituted imidazol-2-ylidene ligands were synthesized by reactions of Cp?FeN(SiMe3)2 (Cp?: η5-C5Me5) with the corresponding imidazolium iodides. These iron complexes exhibited high catalytic performance for dehydrogenation of ammonia-borane in the presence of KN(SiMe3)2. The structure of an active species was determined by its NMR and high-resolution mass spectra and also by isolation of its CO adduct.

Synthesen substituierter 9,9-Bis(n-butyl)dibenzostannole

Syntheses of the five 9,9-bis(n-butyl)dibenzostannoles are reported, which are each symmetrically disubstituted by two F3C-, CH3O-, (CH3)3C-substituents in the 3- and 6-positions or by two F3C-, CH3O-substituents in the 2- and 7-positions of the benzo rings.