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Benzene, 1,2-dimethoxy-4-(methoxymethoxy)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 133129-56-3 Structure
  • Basic information

    1. Product Name: Benzene, 1,2-dimethoxy-4-(methoxymethoxy)-
    2. Synonyms:
    3. CAS NO:133129-56-3
    4. Molecular Formula: C10H14O4
    5. Molecular Weight: 198.219
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 133129-56-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Benzene, 1,2-dimethoxy-4-(methoxymethoxy)-(CAS DataBase Reference)
    10. NIST Chemistry Reference: Benzene, 1,2-dimethoxy-4-(methoxymethoxy)-(133129-56-3)
    11. EPA Substance Registry System: Benzene, 1,2-dimethoxy-4-(methoxymethoxy)-(133129-56-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 133129-56-3(Hazardous Substances Data)

133129-56-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 133129-56-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,1,2 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 133129-56:
(8*1)+(7*3)+(6*3)+(5*1)+(4*2)+(3*9)+(2*5)+(1*6)=103
103 % 10 = 3
So 133129-56-3 is a valid CAS Registry Number.

133129-56-3Relevant articles and documents

Studies toward the total synthesis of popolohuanone E: enantioselective synthesis of 8-O-methylpopolohuanone E.

Katoh,Nakatani,Shikita,Sampe,Ishiwata,Ohmori,Nakamura,Terashima

, p. 2701 - 2704 (2001)

[structure: see text]. 8-O-methylpopolohuanone E (2) was synthesized in a highly convergent manner starting from the cis-fused decalin derivative accessible from the (-)-Wieland-Miescher ketone analogue. The synthetic method features a biogenetic-type annulation of the phenolic and quinone segments to regioselectively construct the central tricyclic ring system as the key step.

Construction of BCDEF Core of Andilesin C

Zhu, Guili,Zhou, Chengying,Chen, Song,Fu, Shaomin,Liu, Bo

, p. 7809 - 7812 (2019)

A synthetic study toward the BCDEF core skeleton of andilesin C is presented. Key elements involved iron-promoted intramolecular perezone-type [5 + 2] cycloaddition to install the BCD ring system simultaneously in a one-step, copper-catalyzed intramolecul

Design, synthesis, and evaluation of A-ring-modified lamellarin N analogues as noncovalent inhibitors of the EGFR T790M/L858R mutant

Fukuda, Tsutomu,Umeki, Teppei,Tokushima, Keiji,Xiang, Gao,Yoshida, Yuki,Ishibashi, Fumito,Oku, Yusuke,Nishiya, Naoyuki,Uehara, Yoshimasa,Iwao, Masatomo

supporting information, p. 6563 - 6580 (2017/11/17)

A series of A-ring-modified lamellarin N analogues were designed, synthesized, and evaluated as potential noncovalent inhibitors of the EGFR T790M/L858R mutant, a causal factor in the drug-resistant non-small cell lung cancer. Several water-soluble ammonium- or guanidinium-tethered analogues exhibited good kinase inhibitory activities. The most promising analogue, 14f, displayed an excellent inhibitory profile against the T790M/L858R mutant [IC50 (WT) = 31.8 nM; IC50 (T790M/L858R) = 8.9 nM]. The effects of A-ring-substituents on activity were rationalized by docking studies.

InCl3-mediated intramolecular Friedel-Crafts-type cyclization and its application to construct the [6-7-5-6] tetracyclic scaffold of liphagal

Jiang, Hao,Tian, Lufeng,Li, Zhentao,Liu, Qi,Li, Chuangchuang,Yao, Xinsheng,Yang, Zhen

experimental part, p. 36 - 42 (2012/03/22)

A unified strategy toward the construction of the [5.7.6]tricyclic skeleton of liphagal is reported, featuring InCl3-mediated intramolecular Friedel-Crafts-type cyclization.

Chemistry of renieramycins. Part 12: An improved total synthesis of (±)-renieramycin G

Yokoya, Masashi,Shinada-Fujino, Kimiko,Yoshida, Saiko,Mimura, Masahiro,Takada, Hiroki,Saito, Naoki

experimental part, p. 4166 - 4181 (2012/07/28)

An improved total synthesis of (±)-renieramycin G (1g) from readily available 2-hydroxy-3-methyl-4,5-dimethoxybenzaldehyde (7) in 21 steps (6.3% overall yield) is described. The synthesis features the concise construction of a pentacyclic framework using the stereoselective Pictet-Spengler type cyclization reaction of lactam (25) with ethyl diethoxyacetate, followed by the base-catalyzed epimerization of the C-1 stereo center of aldehyde (30a). The results of cytotoxicity studies are also presented.

PYRIDINYL- AND PYRAZINYL -METHYLOXY - ARYL DERIVATIVES USEFUL AS INHIBITORS OF SPLEEN TYROSINE KINASE (SYK)

-

Page/Page column 46, (2012/10/07)

A compound of formula (I) or a salt thereof; which is an inhibitor of spleen tyrosine kinase (SYK) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast cells, macrophages, and B-cells and related inflammato

NOVEL COMPOUNDS

-

Page/Page column 22, (2012/09/22)

A compound of formula (I): or a salt thereof; which is an inhibitor of spleen tyrosine kinase (SYK) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast cells, macrophages, and B-cells and related inflammat

Sporolide B: Synthetic studies

Gladding, Jeffery A.,Bacci, James P.,Shaw, Scott A.,Smith III, Amos B.

scheme or table, p. 6697 - 6706 (2011/10/01)

Studies directed toward the synthesis of the architecturally complex marine natural product sporolide B are described. Synthetic analysis suggested advanced hydroquinone and benzodiquinane fragments, which upon elaboration were successfully united via an

Total synthesis of lespedezavirgatol

Qi, Jinping,Deng, Hongzhu,Cao, Derong

experimental part, p. 2547 - 2550 (2011/10/05)

Lespedezavirgatol, a novel 2-phenylbenzofuran compound which was isolated from Lespedeza virgata, was firstly synthesized from pyrogallic acid and 3,4-dimethoxyphenol as starting materials with 8 steps. The key steps for the total synthesis were the selective iodination at 3-position of 1,2-dimethoxy-4-methoxymethoxybenzene and the Sonogashira cross-coupling reaction between 4-iodo-2-methoxybenzene-1,3-diol and 2-ethynyl-3,4-dimethoxy-1- (methoxy-methoxy)-benzene.

Synthesis of various model compounds for the central tricyclic ring system of popolophuanone E

Ueki, Yasuyuki,Itoh, Masanori,Katoh, Tadashi,Terashima, Shiro

, p. 5719 - 5722 (2007/10/03)

An efficient synthesis of various model compounds 4a-e for the tricyclic core of popolophuanone E (1), a novel marine natural product, was accomplished; the method features highly regioselective annulation of the phenols 5a-e with the 2,3-dichloro-1,4-benzoquinones 7, 7c-e. Preliminary studies definitely demonstrated the feasibility of our designed synthetic strategy for 1 (the phenolic subunit I + the quinone subunit II → 1).

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