13333-91-0

Basic information

• Product Name: 3,6-dimethyl-9H-xanthene
• Synonyms: 3,6-dimethyl-9H-xanthene;Einecs 236-384-3
• CAS NO: 13333-91-0
• Molecular Formula: C₁₅H₁₄O
• Molecular Weight: 210.27106
• EINECS: 236-384-3
• Mol File: 13333-91-0.mol

Chemical Properties

• Boiling Point: 348.2°C at 760 mmHg
• Flash Point: 161.3°C
• Appearance: /
• Density: 1.108g/cm³
• Vapor Pressure: 0.000103mmHg at 25°C
• Refractive Index: 1.601
• CAS DataBase Reference: 3,6-dimethyl-9H-xanthene(CAS DataBase Reference)
• NIST Chemistry Reference: 3,6-dimethyl-9H-xanthene(13333-91-0)
• EPA Substance Registry System: 3,6-dimethyl-9H-xanthene(13333-91-0)

Safety Data

• Hazardous Substances Data: 13333-91-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H14O/c1-10-3-5-12-9-13-6-4-11(2)8-15(13)16-14(12)7-10/h3-8H,9H2,1-2H3

Upstream product

• 50-00-0 formaldehyd 
• 108-39-4 3-methyl-phenol 
• 19814-69-8 3,6-dimethylxanthen-9-one 
• 10034-85-2 hydrogen iodide 
• 1193-18-6 3-methylcyclohexen-2-one 
• 698-27-1 4-methylsalicylaldehyde 
• 7214-50-8 5-methylcyclohex-2-en-1-one 

Relevant articles and documents

Copper-catalyzed aerobic asymmetric cross-dehydrogenative coupling of C(sp3)-H bonds driven by visible light

Asymmetric cross-dehydrogenative coupling (CDC) of C(sp3)-H bonds shows great potential for rapid and stereoselective construction of C-C bonds and use of molecular oxygen as the oxidant for such transformations is appealing in the context of green synthetic methodologies. However, the poor reactivity of oxygen at the ground state and the challenges in controlling the stereochemistry make it extremely difficult to access highly enantioselective aerobic CDC reactions of C(sp3)-H precursors. Herein we report our effort towards this goal via copper-based asymmetric photocatalysis. A chiral-copper catalyst initiates the visible-light-driven oxidative CDC reaction by molecular oxygen, and governs the stereochemistry. In this way, a diastereo- and enantioselective cross-dehydrogenative coupling between carbonyl compounds and xanthene derivatives has been achieved. This work provides an economic and manageable approach to stereoselective C-C bond formation, and demonstrates a potential application of chiral copper catalysts in difficult asymmetric photochemical reactions.

Electrochemically Mediated Direct C(sp3)?H Sulfonylation of Xanthene Derivatives

The construction of C(sp3)-sulfonyl bonds through direct sulfonylation of C(sp3)?H bond presents a number of challenges, so an electrochemical oxidation-induced direct sulfonylation of the xanthene C(sp3)?H bond was developed. Significant advantages of this method are high atom efficiency, functional group tolerance, transition metal- and oxidant-free conditions. The in vitro cytotoxicity of all product is evaluated by MTT assay against human cancer cell lines. The results reveal that most of the compounds 3 da and 3 af have good inhibitory activity on tumor cell lines. (Figure presented.).

Chemokine receptor antagonists

PCT No. PCT/JP97/02548 Sec. 371 Date Jan. 29, 1999 Sec. 102(e) Date Jan. 29, 1999 PCT Filed Jul. 23, 1997 PCT Pub. No. WO98/04554 PCT Pub. Date Feb. 5, 1998The present invention relates to a compound of the general formula: wherein each of R1 and R2 which