133433-62-2

Basic information

• Product Name: 1-ACETYL-5-BROMOINDOLIN-7-AMINE
• Synonyms: 1-ACETYL-5-BROMOINDOLIN-7-AMINE ;1-(7-aMino-5-broMoindolin-1-yl)ethanone;1-Acetyl-7-amino-5-bromoindoline
• CAS NO: 133433-62-2
• Molecular Formula: C₁₀H₁₁BrN₂O
• Molecular Weight: 255.11114
• Mol File: 133433-62-2.mol

Chemical Properties

• Boiling Point: 487.0±45.0 °C(Predicted)
• Appearance: /
• Density: 1.601±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 2.91±0.20(Predicted)
• CAS DataBase Reference: 1-ACETYL-5-BROMOINDOLIN-7-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ACETYL-5-BROMOINDOLIN-7-AMINE(133433-62-2)
• EPA Substance Registry System: 1-ACETYL-5-BROMOINDOLIN-7-AMINE(133433-62-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 133433-62-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-Acetyl-5-bromoindolin-7-amine is used as a building block for the synthesis of pharmaceutical compounds due to its unique molecular structure and the presence of a bromine atom and an acetyl group, which can be leveraged in the development of new drugs.
Used in Medicinal Chemistry Research:
1-Acetyl-5-bromoindolin-7-amine is utilized as a research reagent in medicinal chemistry, where it aids in the exploration of new drug candidates and the understanding of molecular interactions within biological systems.
Used in Chemical and Biological Studies:
As a research reagent, 1-Acetyl-5-bromoindolin-7-amine is employed in various chemical and biological studies to investigate its properties and potential applications, furthering the knowledge of its role in scientific research and development.

Upstream product

• 62368-07-4 1-acetyl-5-bromo-7-nitro-2,3-dihydro-1H-indole 
• 7439-89-6 iron 

Relevant articles and documents

Heterogeneous Iron-Catalyzed Hydrogenation of Nitroarenes under Water-Gas Shift Reaction Conditions

Reduction of various nitroarenes in the presence of heterogeneous iron oxide-based catalyst Fe 2 O 3 /NGr@C under water-gas shift reaction (WGSR) conditions has been demonstrated. The catalytic material is prepared in a straightforward manner via deposition/pyrolysis of iron-phenanthroline complex on carbon support. It shows high chemoselectivity towards the reduction of nitroarenes in the presence of other reducible and/or poisoning-capable functional groups. Hydrogenation is achieved using CO/H 2 O as a hydrogen source. Furthermore, it is demonstrated that the presence of triethylamine additive has a significant positive effect on the rate of reduction.

Cyclic anthranilic acid derivatives and process of preparing the same

The following cyclic anthranilic acid derivative, their acid addition salts or alkali salts thereof represented by a general formula [I] are useful for antirheumatic drug, autoimmune disease curing drug and metabolic bone disease curing drug. STR1 wherein R1 to R6 and X are as defined in claim 1.