1335053-95-6

Basic information

• Product Name: 1,6-dichloro-2,7-naphthyridine
• Synonyms: 1,6-dichloro-2,7-naphthyridine;EOS-61453
• CAS NO: 1335053-95-6
• Molecular Formula: C8H4Cl2N2
• Molecular Weight: 199.03676
• Mol File: 1335053-95-6.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1,6-dichloro-2,7-naphthyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 1,6-dichloro-2,7-naphthyridine(1335053-95-6)
• EPA Substance Registry System: 1,6-dichloro-2,7-naphthyridine(1335053-95-6)

Safety Data

• Hazardous Substances Data: 1335053-95-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1,6-dichloro-2,7-naphthyridine is used as a key intermediate in the synthesis of various pharmaceuticals for its potential antimicrobial and antifungal properties. It contributes to the development of new drugs targeting a range of infections and diseases.
Used in Agrochemical Industry:
In the agrochemical sector, 1,6-dichloro-2,7-naphthyridine is employed as a starting material for the production of pesticides and other agrochemicals. Its antimicrobial properties make it a valuable component in creating effective solutions for crop protection and disease management.
Used in Chemical Industry:
1,6-dichloro-2,7-naphthyridine serves as an important intermediate in the chemical industry, playing a crucial role in the synthesis of a variety of organic compounds. Its unique structure and reactivity make it a valuable building block for creating new and innovative chemical products.
Overall, 1,6-dichloro-2,7-naphthyridine is a versatile and essential compound in multiple industries, particularly in the development and production of pharmaceuticals, agrochemicals, and other organic compounds. Its potential applications and industrial uses highlight its significance in the chemical field.

Upstream product

• 875-35-4 2,6-dichloro-4-methylnicotinonitrile 
• 1175559-53-1 2,6-dichloro-4-[(E)-2-(dimethylamino)ethenyl]pyridine-3-carbonitrile 
• 950746-21-1 6,8-dichloro-2,7-naphthyridin-1(2H)-one 
• 5444-02-0 2,6-dihydroxy-3-cyano-4-methylpyrimidine 

Relevant articles and documents

Wnt SIGNALING INHIBITOR, COMPOSITION, AND COMPOUND AS USE THEREFOR

PROBLEM TO BE SOLVED: To provide an inhibitor for Wnt signaling route. SOLUTION: The present invention provides a compound represented by formula I, and a composition comprising the compound (X1-X8 independently represent CR4 or N; Y1 is H or C (R4)3; Y2 and Y3 independently represent H, halogen or C (R3)3; R1 and R2 independently represent H, halogen, C1-6 alkyl, quinolinyl or the like; R3s independently represent H, halogen, cyano, C1-6 alkyl or the like; R4s independently represent H, halogen, cyano, C1-6 alkoxy or the like). SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT

Inhibiting WNT signal conduction of compound, composition and use thereof (by machine translation)

The invention relates to a having the general formula (1) compounds and compositions thereof, and the use of the compound or composition thereof to inhibit WNT signal transmission method. The compounds of this invention and its composition can effectively inhibit the secretion of WNT protein, inhibit WNT signal conduction, so the WNT-mediated disease with a very good therapeutic effect. . (by machine translation)

TUMOR BIOMARKERS AND USE THEREOF

Disclosed herein are biomarkers related to WNT signal transduction pathway, as well as methods and kits comprising the same. Further, the present disclosure relates to the use of the biomarkers in patient selection, companion diagnostics, and treatment of cancer.

Compound as WNT Signaling Inhibitor, Composition, and Use Thereof

The present invention relates to a compound having the structure of Formula I as inhibitor of WNT signal transduction pathways, as well as a composition comprising the compound. Further, the present invention relates to the use of the compound and the method of inhibiting the WNT signal transduction pathways.

COMPOUNDS FOR TREATMENT OF FIBROSIS DISEASES

The present invention relates to compounds as inhibitor of WNT signal transduction pathway, as well as a composition comprising the same. Further, the present invention relates to the use of the compounds in the treatment of fibrosis. Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process. Fibrosis is the end result of chronic inflammatory reactions induced by a variety of stimuli including persistent infections, autoimmune reactions, allergic responses, chemical insults, radiation, and tissue injury.

COMPOUNDS FOR TREATMENT OF CANCER

The present invention relates to compounds as inhibitor of WNT signal transduction pathway, as well as a composition comprising the same. Further, the present invention relates to the use of the compounds in the treatment of cancer.

COMPOUND AS WNT SIGNALING INHIBITOR, COMPOSITION, AND USE THEREOF

The present invention relates to a compound having the structure of Formula I as inhibitor of WNT signal transduction pathways, as well as a composition comprising the compound. Further, the present invention relates to the use of the compound and the method of inhibiting the WNT signal transduction pathways.