13441-54-8

Basic information

• Product Name: 3-formyl-1-methylpyridinium
• CAS NO: 13441-54-8
• Molecular Formula: C₇H₈NO*I
• Molecular Weight: 122.144
• Mol File: 13441-54-8.mol

Chemical Properties

• CAS DataBase Reference: 3-formyl-1-methylpyridinium(CAS DataBase Reference)
• NIST Chemistry Reference: 3-formyl-1-methylpyridinium(13441-54-8)
• EPA Substance Registry System: 3-formyl-1-methylpyridinium(13441-54-8)

Safety Data

• Hazardous Substances Data: 13441-54-8(Hazardous Substances Data)

Upstream product

• 500-22-1 3-pyridinecarboxaldehyde 
• 74-88-4 methyl iodide 
• 553-53-7 Nicotinic acid hydrazide 
• 5433-39-6 N'-nicotinoylbenzenesulfonohydrazide 

Downstream Products

• 97369-66-9 3-<<(3-Hydroxyphenyl)imino>methyl>-1-methylpyridinium-iodid-N-oxid 
• 97369-63-6 1-Methyl-3-<<(4-methylphenyl)imino>methyl>pyridinium-iodid-N-oxid 
• 97369-64-7 3-<<(4-Methoxyphenyl)imino>methyl>-1-methylpyridinium-iodid-N-oxid 
• 97369-35-2 3-<<(3-Methoxycarbonylphenyl)imino>methyl>-1-methylpyridinium-iodid-N-oxid 
• 7511-14-0 N,N-dimethyl-1H-indole-2-carboxamide 
• 141018-87-3 4-(2-formyl-3-indolyl)-1-methyl-1,4-dihydropyridine-3-carbaldehyde 
• 141018-80-6 6-(2-formyl-3-indolyl)-1-methyl-1,6-dihydropyridine-3-carbaldehyde 
• 41979-55-9 N,N-dimethyl-1-methylindole-2-carboxamide 
• 141018-88-4 4-(2-formyl-1-methyl-3-indolyl)-1-methyl-1,4-dihydropyridine-3-carbaldehyde 
• 141018-81-7 6-(2-formyl-1-methyl-3-indolyl)-1-methyl-1,6-dihydropyridine-3-carbaldehyde 
• 141018-78-2 6-<2--3-indolyl>-1-methyl-1,6-dihydropyridine-3-carbaldehyde 
• 141018-79-3 6-<2--1-methyl-3-indolyl>-1-methyl-1,6-dihydropyridine-3-carbaldehyde 
• 1207187-30-1 N-methylpyridinium-3-carboxaldehyde bis(trifluoromethanesulfonyl)amide 

Relevant articles and documents

Constitutional dynamic systems of ionic and molecular liquids

The ionic liquids N-methylpyridinium-2-carboxaldehyde Tf2N - and N-methylpyridinium-3-carboxaldehyde Tf2N- form readily-reversible covalent bonds with protic nucleophiles, creating all-liquid constitutionally dynamic materials. The Royal Society of Chemistry 2009.

Synthesis of piperidine derivatives by reduction of pyridinium salts

Piperidine derivatives 1a-e and 2a-f have been prepared by the reduction of 3-and 4-substituted pyridinium salts with NaBH4 in moderate to excellent yields. The reactions regioselectively give 1,2,5,6-tetrahydropyridines, and the yields depend greatly upon the nature of substituents on the phenyl ring and on the nitrogen atom, the nature and the position of the substituents on the pyridyl ring, and the chain length between the aryloxy and the pyridyl groups. Copyright Taylor & Francis Group, LLC.

Hydrates of quaternary ammonium aldehydes as potential reactivators of sarin-inhibited acetylcholinesterase

Synthesis of 2-(5a), 3-(5b) and 4-formyl-1-methylpyridinium iodides (5c) and (2,2-dihydroxyethy)trimethylammonium chloride (6a) is described. In aqueous solution aldehydes 5 exist predominantly as hydrates - geminal diols 7. The ability of the geminal diols 6a and 7 to reactivate acetylcholinesterase inhibited by isopropyl methylflourophosphonate (Sarin) was tested in vitro. Although compounds 6a and 7 exhibit an affinity towards the acetylcholinesterase bonding site comparable with that of the natural substrate acetylcholine, their reactivation ability was negligible. Second-order rate constants for cleavage of 4-nitrophenyl diphenyl phosphate (PNPDPP) with anions of the studied geminal diols were measured in order to determine their nucleophilicity.