134965-78-9

Basic information

• Product Name: 3-Isoxazolemethanol,5-amino--alpha--ethyl--alpha--methyl-(9CI)
• Synonyms: 3-Isoxazolemethanol,5-amino--alpha--ethyl--alpha--methyl-(9CI)
• CAS NO: 134965-78-9
• Molecular Formula: C7H12N2O2
• Molecular Weight: 156.18238
• Product Categories: OXAZOLE
• Mol File: 134965-78-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Isoxazolemethanol,5-amino--alpha--ethyl--alpha--methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Isoxazolemethanol,5-amino--alpha--ethyl--alpha--methyl-(9CI)(134965-78-9)
• EPA Substance Registry System: 3-Isoxazolemethanol,5-amino--alpha--ethyl--alpha--methyl-(9CI)(134965-78-9)

Safety Data

• Hazardous Substances Data: 134965-78-9(Hazardous Substances Data)

Usage

General Description

3-Isoxazolemethanol,5-amino--alpha--ethyl--alpha--methyl-(9CI) is a chemical compound with the molecular formula C7H10N2O2. It is a derivative of isoxazole and contains an amino, ethyl, and methyl group. It is a white to off-white crystalline powder and is commonly used as a building block in organic synthesis and pharmaceutical research. 3-Isoxazolemethanol,5-amino--alpha--ethyl--alpha--methyl-(9CI) has potential applications in medicinal chemistry due to its structural features and potential pharmacological activities. It is important to handle this chemical with care and in accordance with safety guidelines to prevent any harmful effects on health and the environment.

Upstream product

• 32837-88-0 4-hydroxy-4-methylhex-2-ynenitrile 
• 5470-11-1 hydroxylamine hydrochloride 

Relevant articles and documents

5-Amino-3-imino-2,3-dihydrofurans and 3-Amino-5-imino-2,5-dihydrofurans from 4,4-Dialkyl-4-hydroxybut-2-ynenitriles

A novel general synthesis of the dihydrofurans 4 and 3b with nitrogen substituents in the 3- and 5-positions from 4,4-dialkyl-4-hydroxybut-2-ynenitriles 1 and primary and secondary amines is described.A 5-amino group reacts further with unchanged, or an excess of, hydroxybutynenitrile to give the difurylimines 6.

Allenes. Part 42. Nucleophilic Addition of Hydroxylamine to Allenic and Acetylenic Nitriles; Synthesis of 3-Alkyl-5-amino, 5-Amino-3-phenyl, and 3-Amino-5-phenyl-isoxazoles

Hydroxylamine adds to allenic nitriles to give 3-alkyl-5-aminoisoxazoles in excellent yield.Hydroxyacetylenic nitriles similarly give 5-amino-3-(1-hydroxyalkyl)isoxazoles.Phenylpropynenitrile under varying conditions of temperature and solvent yields mainly 5-amino-3-phenylisoxazole with varying amounts of 3-amino-5-phenylisoxazole as a by-product.