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13519-90-9

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Photoinduced Copper(I)-Catalyzed Cyanation of Aromatic Halides at Room Temperature
The first photoinduced copper(I)-catalyzed cyanation of aromatic halides at room temperature has been developed. The sp2 cyanation reaction exhibits outstanding tolerance to functional groups including primary amines and carboxylic acids, and chemoselectivity to SN2-reactive alkyl chlorides. Mechanistic investigations indicate that the reaction occurs via a single-electron transfer (SET) between the aryl halide and an excited copper(I) cyanide catalytic intermediate. (Figure presented.).
Kim, Kicheol,Hong, Soon Hyeok
supporting information
p. 2345 - 2351
(2017/07/22)

FACTOR IXA INHIBITORS
In its many embodiments, the present invention provides a novel class of benzamide compounds represented by Formula (I) or pharmaceutically acceptable salts or solvates thereof, or pharmaceutical compositions comprising one or more said compounds or pharmaceutically acceptable salts or solvates thereof, and methods for using said compounds or pharmaceutically acceptable salts or solvates thereof for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.
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Page/Page column 102; 142

(2015/11/09)

ANTIPARASITIC AGENTS
The present invention relates to compounds of the formula (I) or a tautomer or prodrug thereof, or a pharmaceutically acceptable salt of said compound, tautomer or prodrug, wherein: R1, R2, R3, R4 and R5 are each independently selected from H, halo, CN, CF3 and CONH2; compositions containing such compounds and the uses of such compounds as antiparasitic agents.
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Page/Page column 22

(2008/12/07)

3-AMINOINDAZOLES
Novel 3-aminoindazoles of formula (I) are SGK-inhibitors and can be used for treating SGK-related diseases and illnesses such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonary hypertonia, cardiovascular diseases and renal diseases, and generally any type of fibroses and inflammatory processes.
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(2008/06/13)

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Chemical Properties

Boiling Point: 241.9 °C at 760 mmHg
Flash Point:100.1 °C
Density: 1.27 g/cm³
Storage Temp.:Sealed in dry,Room Temperature
Vapor Pressure: 0.0349mmHg at 25°C
Refractive Index: 1.538
PSA: 47.58000
LogP: 1.56906

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