13519-90-9

Basic information

• Product Name: 4-Fluoroisophthalonitrile
• Synonyms: 4-Fluoro-1,3-benzenedicarbonitrile;4-Fluoroisophthalonitrile 99%;4-Fluorobenzene-1,3-dicarbonitrile
• CAS NO: 13519-90-9
• Molecular Formula: C₈H₃FN₂
• Molecular Weight: 146.1212
• Product Categories: Fluorine series
• Mol File: 13519-90-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 241.9 °C at 760 mmHg
• Flash Point: 100.1 °C
• Appearance: /
• Density: 1.27 g/cm³
• Vapor Pressure: 0.0349mmHg at 25°C
• Refractive Index: 1.538
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-Fluoroisophthalonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Fluoroisophthalonitrile(13519-90-9)
• EPA Substance Registry System: 4-Fluoroisophthalonitrile(13519-90-9)

Safety Data

• Hazardous Substances Data: 13519-90-9(Hazardous Substances Data)

Usage

General Description

4-Fluoroisophthalonitrile is a chemical compound with the molecular formula C8H3FNO2. It is a white crystalline solid that is mainly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 4-Fluoroisophthalonitrile is also used in the production of dyes and pigments. It is a versatile building block in organic synthesis and is known for its ability to undergo various chemical reactions to form complex molecular structures. Due to its usefulness in the pharmaceutical and agrochemical industries, 4-Fluoroisophthalonitrile is considered to be an important and valuable chemical compound.

InChI:InChI=1/C8H3FN2/c9-8-2-1-6(4-10)3-7(8)5-11/h1-3H

Upstream product

• 218301-22-5 2-fluoro-5-formylbenzonitrile 
• 146137-79-3 4-fluoro-3-formylbenzonitrile 
• 773837-37-9 sodium cyanide 
• 351003-36-6 2-fluoro-5-iodobenzonitrile 
• 13520-12-2 4-chloro-isophthalic acid diamide 
• 13520-10-0 4-Chlor-isophthalaldehyd-dioxim 
• 13520-08-6 1-chloro-2,4-bis-dichloromethyl-benzene 
• 2845-85-4 4-chloroisophthalic acid 
• 95-66-9 2,4-dimethylchlorobenzene 
• 4387-30-8 4-chloro-1,3-benzenedicarbonitrile 
• 871709-86-3 4-fluoro-3-(hydroxyimino-methyl)-benzonitrile 

Downstream Products

• 1262328-71-1 4-(4-formyl-2-methoxyphenoxy)isophthalonitrile 
• 1375461-31-6 JS-59-145 
• 871709-87-4 3-amino-5-cyano-indazol-1-carboxylic acid-tert-butyl ester 
• 871709-89-6 3-amino-5-[(3-chloro-benzoylamino)-methyl]-indazol-1-carboxylic acid-tert-butyl ester 
• 871708-01-9 N-(3-amino-1H-indazol-5-ylmethyl)-3-chloro-benzamide hydrochloride 

Relevant articles and documents

Photoinduced Copper(I)-Catalyzed Cyanation of Aromatic Halides at Room Temperature

The first photoinduced copper(I)-catalyzed cyanation of aromatic halides at room temperature has been developed. The sp2 cyanation reaction exhibits outstanding tolerance to functional groups including primary amines and carboxylic acids, and chemoselectivity to SN2-reactive alkyl chlorides. Mechanistic investigations indicate that the reaction occurs via a single-electron transfer (SET) between the aryl halide and an excited copper(I) cyanide catalytic intermediate. (Figure presented.).

ANTIPARASITIC AGENTS

The present invention relates to compounds of the formula (I) or a tautomer or prodrug thereof, or a pharmaceutically acceptable salt of said compound, tautomer or prodrug, wherein: R1, R2, R3, R4 and R5 are each independently selected from H, halo, CN, CF3 and CONH2; compositions containing such compounds and the uses of such compounds as antiparasitic agents.