13519-90-9

Usage

Uses

Used in Pharmaceutical Industry:
4-Fluoroisophthalonitrile is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic applications. Its reactivity allows for the creation of diverse molecular entities that can address various medical needs.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Fluoroisophthalonitrile is employed as an intermediate in the production of agrochemicals, facilitating the development of innovative compounds designed to enhance crop protection and yield.
Used in Dye and Pigment Production:
4-Fluoroisophthalonitrile is utilized as a building block in the creation of dyes and pigments, where its chemical properties contribute to the formation of colorants with specific characteristics for use in various industries, including textiles, plastics, and printing inks.
Used in Organic Synthesis:
As a versatile component in organic synthesis, 4-Fluoroisophthalonitrile is used to construct complex molecular structures that can be applied across different chemical and material science domains, further expanding its utility and relevance in scientific research and industrial applications.

InChI:InChI=1/C8H3FN2/c9-8-2-1-6(4-10)3-7(8)5-11/h1-3H

Upstream product

• 2845-85-4 4-chloroisophthalic acid 
• 146137-79-3 4-fluoro-3-formylbenzonitrile 
• 773837-37-9 sodium cyanide 
• 351003-36-6 2-fluoro-5-iodobenzonitrile 
• 218301-22-5 2-fluoro-5-formylbenzonitrile 
• 871709-86-3 4-fluoro-3-(hydroxyimino-methyl)-benzonitrile 
• 13520-12-2 4-chloro-isophthalic acid diamide 
• 13520-10-0 4-Chlor-isophthalaldehyd-dioxim 
• 13520-08-6 1-chloro-2,4-bis-dichloromethyl-benzene 
• 95-66-9 2,4-dimethylchlorobenzene 
• 4387-30-8 4-chloro-1,3-benzenedicarbonitrile 

Downstream Products

• 871709-87-4 3-amino-5-cyano-indazol-1-carboxylic acid-tert-butyl ester 
• 871709-89-6 3-amino-5-[(3-chloro-benzoylamino)-methyl]-indazol-1-carboxylic acid-tert-butyl ester 
• 871708-01-9 N-(3-amino-1H-indazol-5-ylmethyl)-3-chloro-benzamide hydrochloride 

Relevant academic research and scientific papers

Photoinduced Copper(I)-Catalyzed Cyanation of Aromatic Halides at Room Temperature

The first photoinduced copper(I)-catalyzed cyanation of aromatic halides at room temperature has been developed. The sp2 cyanation reaction exhibits outstanding tolerance to functional groups including primary amines and carboxylic acids, and chemoselectivity to SN2-reactive alkyl chlorides. Mechanistic investigations indicate that the reaction occurs via a single-electron transfer (SET) between the aryl halide and an excited copper(I) cyanide catalytic intermediate. (Figure presented.).

FACTOR IXA INHIBITORS

In its many embodiments, the present invention provides a novel class of benzamide compounds represented by Formula (I) or pharmaceutically acceptable salts or solvates thereof, or pharmaceutical compositions comprising one or more said compounds or pharmaceutically acceptable salts or solvates thereof, and methods for using said compounds or pharmaceutically acceptable salts or solvates thereof for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.

ANTIPARASITIC AGENTS

The present invention relates to compounds of the formula (I) or a tautomer or prodrug thereof, or a pharmaceutically acceptable salt of said compound, tautomer or prodrug, wherein: R1, R2, R3, R4 and R5 are each independently selected from H, halo, CN, CF3 and CONH2; compositions containing such compounds and the uses of such compounds as antiparasitic agents.

3-AMINOINDAZOLES

Novel 3-aminoindazoles of formula (I) are SGK-inhibitors and can be used for treating SGK-related diseases and illnesses such as diabetes, obesity, metabolic syndrome (dyslipidaemia), systemic and pulmonary hypertonia, cardiovascular diseases and renal diseases, and generally any type of fibroses and inflammatory processes.